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Feasibility of Reduced Iodine Loads for Vascular Assessment Prior to Transcatheter Aortic Valve Implantation (TAVI) Using Spectral Detector CT.
Schuppert, Christopher; Salatzki, Janek; André, Florian; Riffel, Johannes; Mangold, David L; Melzig, Claudius; Hagar, Muhammad Taha; Kauczor, Hans-Ulrich; Weber, Tim F; Rengier, Fabian; Do, Thuy D.
Afiliación
  • Schuppert C; Department of Diagnostic and Interventional Radiology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg im Breisgau, Germany.
  • Salatzki J; Clinic of Diagnostic and Interventional Radiology, Heidelberg University Hospital, 69120 Heidelberg, Germany.
  • André F; Clinic of Cardiology, Angiology and Pneumology, Heidelberg University Hospital, 69120 Heidelberg, Germany.
  • Riffel J; Clinic of Cardiology, Angiology and Pneumology, Heidelberg University Hospital, 69120 Heidelberg, Germany.
  • Mangold DL; Department of Cardiology and Angiology, Robert Bosch Hospital, 70376 Stuttgart, Germany.
  • Melzig C; Clinic of Diagnostic and Interventional Radiology, Heidelberg University Hospital, 69120 Heidelberg, Germany.
  • Hagar MT; Clinic of Diagnostic and Interventional Radiology, Heidelberg University Hospital, 69120 Heidelberg, Germany.
  • Kauczor HU; Department of Diagnostic and Interventional Radiology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg im Breisgau, Germany.
  • Weber TF; Clinic of Diagnostic and Interventional Radiology, Heidelberg University Hospital, 69120 Heidelberg, Germany.
  • Rengier F; Clinic of Diagnostic and Interventional Radiology, Heidelberg University Hospital, 69120 Heidelberg, Germany.
  • Do TD; Clinic of Diagnostic and Interventional Radiology, Heidelberg University Hospital, 69120 Heidelberg, Germany.
Diagnostics (Basel) ; 14(9)2024 Apr 24.
Article en En | MEDLINE | ID: mdl-38732294
ABSTRACT
Reduced iodine loads for computed tomography (CT)-based vascular assessment prior to transcatheter aortic valve implantation (TAVI) may be feasible in conjunction with a spectral detector CT scanner. This prospective single-center study considered 100 consecutive patients clinically referred for pre-TAVI CT. They were examined on a dual-layer detector CT scanner to obtain an ECG-gated cardiac scan and a non-ECG-gated aortoiliofemoral scan. Either a standard contrast media (SCM) protocol using 80 mL Iohexol 350 mgI/mL (iodine load 28 gI) or a body-mass-index adjusted reduced contrast media (RCM) protocol using 40-70 mL Iohexol 350 mgI/mL (iodine load 14-24.5 gI) were employed. Conventional images and virtual monoenergetic images at 40-80 keV were reconstructed. A threshold of 250 HU was set for sufficient attenuation along the arterial access pathway. A qualitative assessment used a five-point Likert scale. Sufficient attenuation in the thoracic aorta was observed for all patients in both groups using conventional images. In the abdominal, iliac, and femoral segments, sufficient attenuation was observed for the majority of patients when using virtual monoenergetic images (SCM 96-100% of patients, RCM 88-94%) without statistical difference between both groups. Segments with attenuation measurements below the threshold remained qualitatively assessable as well. Likert scores were 'excellent' for virtual monoenergetic images 50 keV and 55 keV in both groups (RCM 1.2-1.4, SCM 1.2-1.3). With diagnostic image quality maintained, it can be concluded that reduced iodine loads of 14-24.5 gI are feasible for pre-TAVI vascular assessment on a spectral detector CT scanner.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Diagnostics (Basel) Año: 2024 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Diagnostics (Basel) Año: 2024 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Suiza