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Dengue virus serotypes and related factors in children with dengue hemorrhagic fever in Southern Vietnam.
Quang Tran, Khai; Hung Pham, Van; Thi Ngoc Tran, Trieu; Thao Mai, Chi; Kieu Anh Pham, Tho; Hoang Ngo, Toan; Bui Thai Nguyen, Huy; Manh Nguyen, Cuong; Van Duong, Hieu; Minh Nguyen, Phuong.
Afiliación
  • Quang Tran K; Department of Pediatrics, Can Tho University of Medicine and Pharmacy, Can Tho City 90000, Vietnam.
  • Hung Pham V; Laboratory of Nam Khoa Biotek Company, Vietnam Research and Development Institute of Clinical Microbiology, Ho Chi Minh City 700000, Vietnam.
  • Thi Ngoc Tran T; Department of Pediatrics, Can Tho University of Medicine and Pharmacy, Can Tho City 90000, Vietnam.
  • Thao Mai C; Department of Infectious Diseases Prevention, Center for Disease Control of Kien Giang Province, Rach Gia City 91100, Vietnam.
  • Kieu Anh Pham T; Department of Physiology, Can Tho University of Medicine and Pharmacy, Can Tho City 90000, Vietnam.
  • Hoang Ngo T; Department of Internal Medicine, Can Tho University of Medicine and Pharmacy, Can Tho City 90000, Vietnam.
  • Bui Thai Nguyen H; Department of Infectious Diseases, Can Tho University of Medicine and Pharmacy, Can Tho City 90000, Vietnam.
  • Manh Nguyen C; Department of Pediatrics, Military Hospital 103, Vietnam Military Medical University, Hanoi 100000, Vietnam.
  • Van Duong H; Can Tho Children's Hospital, Can Tho City 90000, Vietnam.
  • Minh Nguyen P; Department of Pediatrics, Can Tho University of Medicine and Pharmacy, Can Tho City 90000, Vietnam.
J Infect Dev Ctries ; 18(4): 495-500, 2024 Apr 30.
Article en En | MEDLINE | ID: mdl-38728633
ABSTRACT

INTRODUCTION:

After the Coronavirus Disease 2019 pandemic, a high number of cases and severe dengue in children were reported in some provinces in the south of Vietnam. This study aimed to determine the distribution of dengue virus serotypes and their correlation with demographic factors, disease severity, clinical manifestations, and laboratory findings.

METHODOLOGY:

This study employed a cross-sectional design. Ninety-six dengue-infected children admitted to Can Tho Children's Hospital between October 2022 and March 2023 were included. Confirmation of dengue infection was achieved through the real-time polymerase chain reaction (RT-PCR).

RESULTS:

Among the identified serotypes, DENV-2 accounted for the highest proportion (71.87%), followed by DENV-1 (23.96%), and DENV-4 (4.17%). DENV-3 was not detected. No significant demographic, disease severity, or laboratory differences were observed among the identified dengue serotypes. However, DENV-2 was associated with a higher occurrence of mucous membrane hemorrhages and gastrointestinal bleeding compared to other serotypes.

CONCLUSIONS:

Although DENV-2 was the most prevalent serotype responsible for dengue in children in southern Vietnam, it did not lead to more severe cases compared to other serotypes. This finding is crucial for evaluating the illness's prognosis.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Dengue Grave / Virus del Dengue / Serogrupo Límite: Adolescent / Child / Child, preschool / Female / Humans / Infant / Male País/Región como asunto: Asia Idioma: En Revista: J Infect Dev Ctries Asunto de la revista: DOENCAS TRANSMISSIVEIS Año: 2024 Tipo del documento: Article País de afiliación: Vietnam Pais de publicación: Italia
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Dengue Grave / Virus del Dengue / Serogrupo Límite: Adolescent / Child / Child, preschool / Female / Humans / Infant / Male País/Región como asunto: Asia Idioma: En Revista: J Infect Dev Ctries Asunto de la revista: DOENCAS TRANSMISSIVEIS Año: 2024 Tipo del documento: Article País de afiliación: Vietnam Pais de publicación: Italia