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Pain control and neonatal outcomes in 211 women under epidural anesthesia during childbirth at high altitude in Qinghai, China.
Wang, Pengxia; Li, Kaihui; Wu, Dongliang; Cheng, Sen; Zeng, Yinying; Gao, Peng; Wang, Zhibing; Liu, Shanshan.
Afiliación
  • Wang P; Department of Anesthesiology, Affiliated Chenggong Hospital of Xiamen University, Xiamen, China.
  • Li K; Department of Anesthesiology, Affiliated Chenggong Hospital of Xiamen University, Xiamen, China.
  • Wu D; Department of Anesthesiology, Affiliated Chenggong Hospital of Xiamen University, Xiamen, China.
  • Cheng S; Department of Anesthesiology, Affiliated Chenggong Hospital of Xiamen University, Xiamen, China.
  • Zeng Y; Department of Anesthesiology, Affiliated Chenggong Hospital of Xiamen University, Xiamen, China.
  • Gao P; Department of Anesthesiology, Affiliated Chenggong Hospital of Xiamen University, Xiamen, China.
  • Wang Z; Department of Medical Service, Affiliated Chenggong Hospital of Xiamen University, Xiamen, Fujian, China.
  • Liu S; Department of Anesthesiology, Affiliated Chenggong Hospital of Xiamen University, Xiamen, China.
Front Med (Lausanne) ; 11: 1361777, 2024.
Article en En | MEDLINE | ID: mdl-38725470
ABSTRACT

Background:

High altitudes are characterized by low-pressure oxygen deprivation. This is further exacerbated with increasing altitude. High altitudes can be associated with reduced oxygenation, which in turn, can affect labor, as well as maternal and fetal outcomes. Epidural anesthesia can significantly relieve labor pain. This study aimed to assess the effects of elevation gradient changes at high altitude on the analgesic effect of epidural anesthesia, labor duration, and neonatal outcomes.

Methods:

We divided 211 women who received epidural anesthesia into groups according to varying elevation of their residence (76 in Xining City, mean altitude 2,200 m; 63 in Haibei Prefecture, mean altitude 3,655 m; and 72 in Yushu Prefecture, mean altitude 4,493 m). The analgesic effect was assessed using a visual analog scale (VAS). Labor duration was objectively recorded. The neonatal outcome was assessed using Apgar scores and fetal umbilical artery blood pH.

Results:

VAS scores among the three groups did not differ significantly (p > 0.05). The neonatal Apgar scores in descending order were Xining group > Haibei group > Yushu group (p < 0.05). The stage of labor was similar among the three groups (p > 0.05). Fetal umbilical artery blood pH in descending order were Xining group > Haibei group > Yushu group (p < 0.05).

Conclusion:

Elevation gradient changes in highland areas did not affect the efficacy of epidural anesthesia or labor duration. However, neonatal outcomes were affected.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Front Med (Lausanne) Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Front Med (Lausanne) Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Suiza