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A Subjective Assessment of Chemotherapy Drug-Induced Taste and Smell Alteration in Non-head and Neck Cancer Patients: A Questionnaire-Based Cross-Sectional Study.
Yadav, Nidhi; Mittal, Swati; Reddy, Prashanthi; Parihar, Ajay; Agrawal, Saloni; Mandlik, Rashi; Sharma, Arun D.
Afiliación
  • Yadav N; Oral Medicine and Radiology, Government College of Dentistry, Indore, Indore, IND.
  • Mittal S; Pediatric and Preventive Dentistry, Government Dental College and Hospital, Ahmedabad, IND.
  • Reddy P; Oral Medicine, Government College of Dentistry, Indore, Indore, IND.
  • Parihar A; Oral Medicine and Radiology, Government College of Dentistry, Indore, Indore, IND.
  • Agrawal S; Oral Medicine and Radiology, Government College of Dentistry, Indore, Indore, IND.
  • Mandlik R; Oral Medicine and Radiology, Government College of Dentistry, Indore, Indore, IND.
  • Sharma AD; Oral Medicine and Radiology, Government College of Dentistry, Indore, Indore, IND.
Cureus ; 16(4): e57787, 2024 Apr.
Article en En | MEDLINE | ID: mdl-38721225
ABSTRACT

OBJECTIVE:

This study aimed to evaluate alterations in taste and smell perceptions among non-head and neck cancer patients receiving chemotherapy, aiming to identify factors influencing these changes.

METHODS:

A cohort of 70 non-head and neck cancer patients undergoing one to four cycles or more than four cycles, over a six-month period, from oncology outpatient clinics was recruited. Participants completed structured taste and smell questionnaires with assistance from interviewers. Demographic data, recurrence history, chemotherapy cycles, drug regimens, and taste and smell perceptions were analyzed using descriptive statistics and chi-square tests.

RESULTS:

The mean age of participants was 46.5 years, with a predominance of females (81.4%) and breast cancer cases (42.9%). Taste changes were more prevalent (62.9%) than smell changes (32.9%) post chemotherapy, particularly among those on combination drug regimens. Salty taste alterations were the most common (30.0%), followed by sweet taste (22.9%) and sour/bitter tastes (14.3%). Moreover, 38.57% of patients reported experiencing dysgeusia, while 30% noted the occurrence of parosmia post chemotherapy.

CONCLUSION:

Chemotherapy-induced alterations in taste and smell significantly impact the quality of life and nutritional status of cancer patients. Despite often being overlooked, these changes warrant increased attention in oncological practice to inform treatment decisions and enhance symptom management, particularly in palliative care settings. Further research is needed to explore the implications of chemosensory alterations on patient outcomes and treatment strategies.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Cureus Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Cureus Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos