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Use of the Systemic Immune-Inflammation Index to Predict Treatment Efficacy in Patients with Bladder Pain Syndrome.
Sahin, Mehmet Fatih; Eseoglu, Esad; Akgul, Murat; Malak, Arzu; Dogan, Cagri; Yazici, Cenk Murat.
Afiliación
  • Sahin MF; Department of Urology, Tekirdag Namik Kemal University, Tekirdag, Turkiye.
  • Eseoglu E; Department of Urology, Tekirdag Namik Kemal University, Tekirdag, Turkiye.
  • Akgul M; Department of Urology, Tekirdag Namik Kemal University, Tekirdag, Turkiye.
  • Malak A; School of Health Nursing Department, Tekirdag Namik Kemal University, Tekirdag, Turkiye.
  • Dogan C; Department of Urology, Tekirdag Namik Kemal University, Tekirdag, Turkiye.
  • Yazici CM; Department of Urology, Tekirdag Namik Kemal University, Tekirdag, Turkiye.
J Coll Physicians Surg Pak ; 34(5): 556-560, 2024 May.
Article en En | MEDLINE | ID: mdl-38720216
ABSTRACT

OBJECTIVE:

To determine the relationship between bladder pain syndrome (BPS) and systemic inflammatory index (SII) and to examine the impact of treatment protocols on it. STUDY

DESIGN:

Observational Study. Place and Duration of the Study Department of Urology, Tekirdag Namik Kemal University, Tekirdag, Turkiye, from January 2017 to December 2022.

METHODOLOGY:

A retrospective analysis was conducted on 30 BPS patients who underwent medical therapy. Upon diagnosis, the patients completed the king's health questionnaire (KHQ), beck depression questionnaire (BDQ), beck anxiety questionnaire (BAQ), and short form (SF-36) quality of life form. Peripheral blood SII was measured. After six months of regular therapy, the SII was recalculated when the patients completed the same forms again. The SII was compared between instances when patients reported more complaints, higher form scores, and instances when they reported fewer and lower scores.

RESULTS:

The patients had a mean age of 46.1 ± 13.6 years, with four males and 26 females. The mean follow-up duration was 76.3 ± 24.5 months. Five patients of KHQ subcategories showed statistically significant decreases following therapy (52 to 39.17, 66.66 to 54.16, 54.40 to 41.07, 75.55 to 58.14, and 60.55 to 40.47). All patients of SF-36 components increased (p = 779, p = 0.393, p = 0.007, p = 0.004, p = 0.008, p = 0.041, p = 0.010, and p = 0.767, respectively). BDQ and BAQ decreased after therapy (11.55 to 11.41 and 11.86 to 11.24, respectively). Lymphocyte count, neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and SII decreased significantly (p = 0.001, 0.019, 0.002 and 0.039, respectively).

CONCLUSION:

SII, lymphocyte count, NLR, and PLR decreased after treatment, similar to BDQ and BAQ. SII is a simple and feasible method for evaluating the treatment efficacy of BPS. KEY WORDS Bladder pain syndrome, Lymphocyte, Neutrophil, Systemic immune inflammation index, Platelet.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cistitis Intersticial Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: J Coll Physicians Surg Pak Asunto de la revista: MEDICINA Año: 2024 Tipo del documento: Article Pais de publicación: Pakistán
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cistitis Intersticial Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: J Coll Physicians Surg Pak Asunto de la revista: MEDICINA Año: 2024 Tipo del documento: Article Pais de publicación: Pakistán