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Prospective 2-Year Course and Predictors of Outcome in Avoidant/Restrictive Food Intake Disorder.
Kambanis, P Evelyna; Tabri, Nassim; McPherson, Iman; Gydus, Julia E; Kuhnle, Megan; Stern, Casey M; Asanza, Elisa; Becker, Kendra R; Breithaupt, Lauren; Freizinger, Melissa; Shrier, Lydia A; Bern, Elana M; Eddy, Kamryn T; Misra, Madhusmita; Micali, Nadia; Lawson, Elizabeth A; Thomas, Jennifer J.
Afiliación
  • Kambanis PE; Massachusetts General Hospital, Boston, Massachusetts; Harvard Medical School Boston, Massachusetts.
  • Tabri N; Carleton University, Ottawa, Ontario, Canada.
  • McPherson I; Massachusetts General Hospital, Boston, Massachusetts.
  • Gydus JE; Massachusetts General Hospital, Boston, Massachusetts.
  • Kuhnle M; Massachusetts General Hospital, Boston, Massachusetts.
  • Stern CM; Massachusetts General Hospital, Boston, Massachusetts; Yeshiva University, Bronx, New York.
  • Asanza E; Massachusetts General Hospital, Boston, Massachusetts.
  • Becker KR; Massachusetts General Hospital, Boston, Massachusetts; Harvard Medical School Boston, Massachusetts.
  • Breithaupt L; Massachusetts General Hospital, Boston, Massachusetts; Harvard Medical School Boston, Massachusetts.
  • Freizinger M; Harvard Medical School Boston, Massachusetts; Boston Children's Hospital, Boston, Massachusetts.
  • Shrier LA; Harvard Medical School Boston, Massachusetts; Boston Children's Hospital, Boston, Massachusetts.
  • Bern EM; Harvard Medical School Boston, Massachusetts; Boston Children's Hospital, Boston, Massachusetts.
  • Eddy KT; Massachusetts General Hospital, Boston, Massachusetts; Harvard Medical School Boston, Massachusetts.
  • Misra M; Massachusetts General Hospital, Boston, Massachusetts; Harvard Medical School Boston, Massachusetts.
  • Micali N; Mental Health Services of the Capital Region of Denmark, Ballerup, Denmark; University College London, London, United Kingdom.
  • Lawson EA; Massachusetts General Hospital, Boston, Massachusetts; Harvard Medical School Boston, Massachusetts.
  • Thomas JJ; Massachusetts General Hospital, Boston, Massachusetts; Harvard Medical School Boston, Massachusetts. Electronic address: jjthomas@mgh.harvard.edu.
Article en En | MEDLINE | ID: mdl-38718975
ABSTRACT

OBJECTIVE:

To evaluate the 2-year course and outcomes of full and subthreshold avoidant/restrictive food intake disorder (ARFID) in youth aged 9 to 23 years at baseline using a prospective longitudinal design to characterize the remission and persistence of ARFID, evaluate diagnostic crossover, and identify predictors of outcome. Greater severity in each ARFID profile-sensory sensitivity, fear of aversive consequences, and lack of interest-was hypothesized to predict greater likelihood of illness persistence, controlling for age, sex, body mass index percentile, ARFID treatment status, and baseline diagnosis.

METHOD:

Participants (N = 100; age range, 9-23 years; 49% female; 91% White) were followed over 2 years. The Pica, ARFID, and Rumination Disorder Interview was used across 3 time points (baseline, year 1, year 2) to measure the severity of each ARFID profile and evaluate illness persistence or remission, and the Eating Disorder Assessment for DSM-5 was used to evaluate diagnostic crossover.

RESULTS:

Across the 2-year follow-up period, half the participants persisted with their original diagnosis, and 3% of participants experienced a diagnostic shift to anorexia nervosa. Greater severity in the sensory sensitivity and lack of interest profiles was associated with higher likelihood of ARFID persistence at year 1 only; greater severity in the fear of aversive consequences profile was associated with higher likelihood of ARFID remission at year 2 only.

CONCLUSION:

Findings underscore the distinctiveness of ARFID from other eating disorders and emphasize its persistence over 2 years. Results also highlight the predictive validity and prognostic value of the ARFID profiles (ie, sensory sensitivity, fear of aversive consequences, lack of interest).
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Am Acad Child Adolesc Psychiatry Asunto de la revista: PEDIATRIA / PSIQUIATRIA Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Am Acad Child Adolesc Psychiatry Asunto de la revista: PEDIATRIA / PSIQUIATRIA Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos