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Skin- and Eco-Friendly Hand Sanitizer: A Novel Composition of Natural Extracts to Prevent the Spread of Respiratory Viruses.
Gomes, Marina; Zuchi, Isabella Dai Prá; Pavi, Catielen Paula; Fongaro, Gislaine; da Silva, Izabella Thaís; Pezzini, Bianca Ramos.
Afiliación
  • Gomes M; Department of Pharmaceutical Sciences, Federal University of Santa Catarina, Florianópolis, SC, 88040-900, Brazil.
  • Zuchi IDP; Department of Pharmaceutical Sciences, Federal University of Santa Catarina, Florianópolis, SC, 88040-900, Brazil.
  • Pavi CP; Department of Microbiology, Immunology and Parasitology, Federal University of Santa Catarina, Florianópolis, SC, 88040-900, Brazil.
  • Fongaro G; Department of Microbiology, Immunology and Parasitology, Federal University of Santa Catarina, Florianópolis, SC, 88040-900, Brazil.
  • da Silva IT; Department of Pharmaceutical Sciences, Federal University of Santa Catarina, Florianópolis, SC, 88040-900, Brazil.
  • Pezzini BR; Department of Microbiology, Immunology and Parasitology, Federal University of Santa Catarina, Florianópolis, SC, 88040-900, Brazil.
AAPS PharmSciTech ; 25(5): 98, 2024 May 07.
Article en En | MEDLINE | ID: mdl-38714600
ABSTRACT
Respiratory diseases caused by viruses are a serious global health threat. Although the use of hand sanitizers containing alcohol and synthetic antiseptic agents is recognized as an effective, simple, and low-cost measure to combat viral transmission, they can harm human health and the environment. Thus, this work aimed to study the efficacy of combining Camellia sinensis and Chamomilla recutita extracts in a skin- and eco-friendly leave-on hand sanitizer to prevent the spread of respiratory viruses. An oil-in-water emulsion containing C. recutita oily extract (5.0%), C. recutita glycolic extract (0.2%) and C. sinensis glycolic extract (5.0%) showed virucidal activity against HAdV-2 (respiratory virus) and two surrogate viruses of SARS-CoV-2 (HSV-1 and MVH-3), showing great potential to prevent the spread of respiratory viruses. These natural extracts combined are also promising to combat a broad spectrum of other viruses, in the form of antiseptic mouthwashes or throat sprays, surface disinfectants, and veterinary products, among others. Complementally, the developed hand sanitizer demonstrated efficacy against bacteria and fungus.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Antivirales / Extractos Vegetales / Desinfectantes para las Manos Límite: Animals / Humans Idioma: En Revista: AAPS PharmSciTech Asunto de la revista: FARMACOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Antivirales / Extractos Vegetales / Desinfectantes para las Manos Límite: Animals / Humans Idioma: En Revista: AAPS PharmSciTech Asunto de la revista: FARMACOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Estados Unidos