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Mean Blood Glucose Level During ICU Hospitalization is a Strong Predictor of the Mortality of COVID-19.
Hu, Jie; Ouyang, Lin; Li, Jinxiu; Li, Xia; Zhong, Yanjun; Hou, Can.
Afiliación
  • Hu J; Critical Care Medicine Center, The Second Xiangya Hospital, Central South University, Changsha, People's Republic of China.
  • Ouyang L; National Clinical Research Center for Metabolic Diseases, Department of Metabolism and Endocrinology, Key Laboratory Diseases Immunology, Ministry of Education, The Second Xiangya Hospital of Central South University, Changsha, Hunan, People's Republic of China.
  • Li J; Department of Critical Care Medicine Center, Guilin Hospital of the Second Xiangya Hospital, The Second Xiangya Hospital of Central South University, Changsha, Hunan, People's Republic of China.
  • Li X; Critical Care Medicine Center, The Second Xiangya Hospital, Central South University, Changsha, People's Republic of China.
  • Zhong Y; National Clinical Research Center for Metabolic Diseases, Department of Metabolism and Endocrinology, Key Laboratory Diseases Immunology, Ministry of Education, The Second Xiangya Hospital of Central South University, Changsha, Hunan, People's Republic of China.
  • Hou C; Critical Care Medicine Center, The Second Xiangya Hospital, Central South University, Changsha, People's Republic of China.
Diabetes Metab Syndr Obes ; 17: 1903-1909, 2024.
Article en En | MEDLINE | ID: mdl-38706805
ABSTRACT

Objective:

To investigate the potential prognostic value of mean blood glucose (MBG) in hospital for prognosis of COVID-19 adult patients in the intensive unit care unit (ICU).

Methods:

A single-site and retrospective study enrolled 107 patients diagnosed as COVID-19 from department of critical care medicine in the Second Xiangya Hospital between October 2022 and June 2023. Demographic information including glucose during ICU hospitalization, comorbidity, clinical data, types of medications and treatment, and clinical outcome were collected. The multivariate logistic and cox regression was used to explore the relationship between blood glucose changes and clinical outcomes of COVID-19 during ICU stay.

Results:

In total, 107 adult patients confirmed with COVID-19 were included. Multivariate logistic regression results showed an increase in MBG was associated with ICU mortality rate. Compared with normal glucose group (MBG <= 7.8 mmol/L), the risk of ICU mortality, 7-day mortality and 28-day mortality from COVID-19 were significantly increased in high glucose group (MBG >7.8mmol/L).

Conclusion:

MBG level during ICU hospitalization was strongly correlated to all-cause mortality and co-infection in COVID-19 patients. These findings further emphasize the importance of overall glucose management in severe cases of COVID-19.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Diabetes Metab Syndr Obes Año: 2024 Tipo del documento: Article Pais de publicación: Nueva Zelanda
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Diabetes Metab Syndr Obes Año: 2024 Tipo del documento: Article Pais de publicación: Nueva Zelanda