Your browser doesn't support javascript.
loading
Evaluation of photoactivated chromophore for keratitis-corneal cross-linking (PACK-CXL) in feline infectious keratitis-patient demographics, treatment protocols, risk factors, and treatment outcome: a retrospective study.
Shukla, Angelie K; Kowalska, Malwina E; Arteaga, Kevin; Crasta, Manuela; Dixon, Christopher; Famose, Frank; Hartnack, Sonja; Pot, Simon Anton.
Afiliación
  • Shukla AK; Ophthalmology Section, Equine Department, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland.
  • Kowalska ME; Section of Epidemiology, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland.
  • Arteaga K; AniCura Vision Vet Veterinary Eye Clinic, Bologna, Italy.
  • Crasta M; AniCura Vision Vet Veterinary Eye Clinic, Bologna, Italy.
  • Dixon C; Veterinary Vision, Penrith, UK.
  • Famose F; Clinique Vétérinaire d'Ophtalmologie Spécialisée, Blagnac, France.
  • Hartnack S; Section of Epidemiology, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland.
  • Pot SA; Ophthalmology Section, Equine Department, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland.
Vet Ophthalmol ; 2024 May 05.
Article en En | MEDLINE | ID: mdl-38706148
ABSTRACT

OBJECTIVES:

To describe patient demographics and treatment protocols in a population of feline patients undergoing photoactivated chromophore for keratitis-corneal cross-linking (PACK-CXL) as an adjunctive treatment for infectious keratitis. Furthermore, to determine the proportion of PACK-CXL treatment success in the population studied, explore risk factors for treatment failure, and provide recommendations for future PACK-CXL clinical studies. MATERIALS AND

METHODS:

Records from four veterinary ophthalmology practices were reviewed to identify eligible patients and extract data. Recorded variables included patient-related factors, ocular examination findings, PACK-CXL protocol parameters, and treatment outcome.

RESULTS:

Records for 153 cats (154 eyes) were included. Median age in the treatment success group was 8 years (interquartile range (IQR) 4-12), with a median ulcer depth of 30% (IQR 30-40). Median age in the treatment failure group was 10.5 years (IQR 4.75-12) with a median ulcer depth of 45.9% (IQR 30-75). Persian cats were the most represented brachycephalic breed (52 out of 64 cats). Modified PACK-CXL protocols were used, including fast energy delivery (134 eyes), and increased fluence (52 eyes). The overall proportion of success was 88% (95% CI 84-93), which was variable between clinics. Eighty-two of 89 mesocephalic cat eyes (92%), and 54 of 65 brachycephalic cat eyes (83%) were classified as treatment successes.

CONCLUSIONS:

PACK-CXL appeared to be a useful, adjunctive therapeutic modality for the treatment of infectious keratitis in the feline patient population presented here. Brachycephalic cats, older cats, and those with deeper ulcers may be at increased risk for treatment failure.
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Vet Ophthalmol Asunto de la revista: MEDICINA VETERINARIA / OFTALMOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Suiza Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Vet Ophthalmol Asunto de la revista: MEDICINA VETERINARIA / OFTALMOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Suiza Pais de publicación: Reino Unido