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Respiratory Rate Oxygenation (ROX) index as predictor of high flow nasal cannula in pediatric patients in pediatric intensive care unit.
Yuniar, Irene; Pudjiadi, Antonius Hocky; Dewi, Rismala; Prawira, Yogi; Puspaningtyas, Niken Wahyu; Tartila, Tartila; Fulki, Sharfina.
Afiliación
  • Yuniar I; Department of Child Health, Cipto Mangunkusumo Hospital, Jakarta, Indonesia. ireneyuniar1@gmail.com.
  • Pudjiadi AH; Department of Child Health, Cipto Mangunkusumo Hospital, Jakarta, Indonesia.
  • Dewi R; Department of Child Health, Cipto Mangunkusumo Hospital, Jakarta, Indonesia.
  • Prawira Y; Department of Child Health, Cipto Mangunkusumo Hospital, Jakarta, Indonesia.
  • Puspaningtyas NW; Department of Child Health, Cipto Mangunkusumo Hospital, Jakarta, Indonesia.
  • Tartila T; Department of Child Health, Cipto Mangunkusumo Hospital, Jakarta, Indonesia.
  • Fulki S; Department of Child Health, Cipto Mangunkusumo Hospital, Jakarta, Indonesia.
BMC Pulm Med ; 24(1): 216, 2024 May 02.
Article en En | MEDLINE | ID: mdl-38698400
ABSTRACT

BACKGROUND:

High-flow nasal cannula (HFNC) is often used in pediatric populations with respiratory distress. In adults, the respiratory-rate oxygenation (ROX) index is used as a predictor of HFNC therapy; however, children have age-associated differences in respiratory rate, thus may not be applicable to children. This study aims to find the reliability of ROX index and modified P-ROX index as predictors of HFNC therapy failure in pediatric patients.

METHODS:

Subjects in this analytical cross-sectional study were taken from January 2023 until November 2023 in Cipto Mangunkusumo Hospital. Inclusion criteria are children aged 1 month to 18 years with respiratory distress and got HFNC therapy. Receiver operating characteristics (ROC) analysis was used to find mP-ROX index cutoff value as a predictor of HFNC failure. The area under curve (AUC) score of mP-ROX index was assessed at different time point.

RESULTS:

A total of 102 patients, with 70% of the population with pneumonia, were included in this study. There are significant differences in the ROX index between the successful and failed HFNC group therapy (p < 0.05). This study suggests that mP-ROX index is not useful as predictor of HFNC therapy in pediatrics. While ROX index < 5.52 at 60 min and < 5.68 at 90 min after HFNC initiation have a sensitivity of 90% and specificity of 71%, sensitivity of 78% and specificity of 76%, respectively.

CONCLUSION:

mP-ROX index is not useful as a predictor of HFNC therapy in pediatrics. Meanwhile, ROX index at 60 min and 90 min after initiation of HFNC is useful as a predictor of HFNC failure.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Terapia por Inhalación de Oxígeno / Unidades de Cuidado Intensivo Pediátrico / Frecuencia Respiratoria / Cánula Límite: Adolescent / Child / Child, preschool / Female / Humans / Infant / Male Idioma: En Revista: BMC Pulm Med Año: 2024 Tipo del documento: Article País de afiliación: Indonesia Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Terapia por Inhalación de Oxígeno / Unidades de Cuidado Intensivo Pediátrico / Frecuencia Respiratoria / Cánula Límite: Adolescent / Child / Child, preschool / Female / Humans / Infant / Male Idioma: En Revista: BMC Pulm Med Año: 2024 Tipo del documento: Article País de afiliación: Indonesia Pais de publicación: Reino Unido