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Prematurity and congenital malformations differ according to the type of pregestational diabetes.
Ballesteros, Monica; Guarque, A; Ingles, M; Vilanova, N; Lopez, M; Martin, L; Jane, M; Puerto, L; Martinez, M; De la Flor, M; Vendrell, J; Megia, A.
Afiliación
  • Ballesteros M; Department of Medicine and Surgery, Rovira i Virgili University, Tarragona, Spain. mballesteros.hj23.ics@gencat.cat.
  • Guarque A; CIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Carlos III Health Institute, Madrid, Spain. mballesteros.hj23.ics@gencat.cat.
  • Ingles M; Department of Obstetrics and Gynecology, University Hospital of Tarragona Joan XXIII, Institut d'Investigació Sanitària Pere Virgili (IISPV), Tarragona, Spain. mballesteros.hj23.ics@gencat.cat.
  • Vilanova N; Department of Medicine and Surgery, Rovira i Virgili University, Tarragona, Spain.
  • Lopez M; CIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Carlos III Health Institute, Madrid, Spain.
  • Martin L; Department of Obstetrics and Gynecology, University Hospital of Tarragona Joan XXIII, Institut d'Investigació Sanitària Pere Virgili (IISPV), Tarragona, Spain.
  • Jane M; CIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Carlos III Health Institute, Madrid, Spain.
  • Puerto L; Department of Obstetrics and Gynecology, University Hospital of Tarragona Joan XXIII, Institut d'Investigació Sanitària Pere Virgili (IISPV), Tarragona, Spain.
  • Martinez M; Institut d'Investigació Sanitària Pere Virgili (IISPV), Tarragona, Spain.
  • De la Flor M; Department of Medicine and Surgery, Rovira i Virgili University, Tarragona, Spain.
  • Vendrell J; Department of Obstetrics and Gynecology, University Hospital of Tarragona Joan XXIII, Institut d'Investigació Sanitària Pere Virgili (IISPV), Tarragona, Spain.
  • Megia A; Department of Medicine and Surgery, Rovira i Virgili University, Tarragona, Spain.
BMC Pregnancy Childbirth ; 24(1): 335, 2024 May 02.
Article en En | MEDLINE | ID: mdl-38698309
ABSTRACT

BACKGROUND:

Diabetes mellitus (DM) is the most common metabolic disorder in pregnancy. Women with Type 2 DM seems to have no better perinatal outcomes than those with Type 1 DM.

METHODS:

Single-center prospective cohort observational study. Pregnant women with diabetes (141 with Type 1 DM and 124 with Type 2 DM) that were followed in the university hospital between 2009 and 2021 were included in this study. Clinical data and obstetric and perinatal outcomes were collected.

RESULTS:

As expected, women with Type 1 DM were younger and had a longer duration of diabetes than women with Type 2 DM. Obesity and chronic hypertension were higher in the group of women with Type 2 DM and their value of HbA1c in the second and third trimesters were lower than in Type 1 DM. No differences in prematurity were found, but more extreme prematurity was observed in Type 2 DM, as well as a higher rate of congenital malformations. The frequency of hypoglycemia and the weight of the newborn was higher in Type 1 DM. The maternal independent factors related to the weight of the newborn were the glycemic control at the third trimester, the weight gain during pregnancy, and pregestational BMI.

CONCLUSIONS:

Newborns born to mothers with Type 1 DM were larger and had a higher frequency of hypoglycemia, while congenital malformations and precocious preterm was more associated to Type 2 DM. Metabolic control, weight gain and pregestational weight were important determinants of both obstetric and neonatal complications.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Embarazo en Diabéticas / Anomalías Congénitas / Nacimiento Prematuro / Diabetes Mellitus Tipo 1 / Diabetes Mellitus Tipo 2 Límite: Adult / Female / Humans / Newborn / Pregnancy Idioma: En Revista: BMC Pregnancy Childbirth Asunto de la revista: OBSTETRICIA Año: 2024 Tipo del documento: Article País de afiliación: España Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Embarazo en Diabéticas / Anomalías Congénitas / Nacimiento Prematuro / Diabetes Mellitus Tipo 1 / Diabetes Mellitus Tipo 2 Límite: Adult / Female / Humans / Newborn / Pregnancy Idioma: En Revista: BMC Pregnancy Childbirth Asunto de la revista: OBSTETRICIA Año: 2024 Tipo del documento: Article País de afiliación: España Pais de publicación: Reino Unido