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Anatomical damages in the spinal nerve roots and the spinal cord after brachial plexus injury: descriptive study from a cohort of consecutive patients who underwent DREZ-lesioning for pain-practical implications.
Georgoulis, George; Neromyliotis, Eleftherios; Sindou, Marc.
Afiliación
  • Georgoulis G; Department of Neurosurgery, General Hospital of Athens "G. Gennimatas", Mesogeion Avenue 154, 11527, Athens, Greece. gdgeorgoulis@gmail.com.
  • Neromyliotis E; Department of Neurosurgery, "Evangelismos" Hospital, University of Athens, Athens, Greece.
  • Sindou M; University of Lyon, Lyon, France.
Acta Neurochir (Wien) ; 166(1): 201, 2024 May 02.
Article en En | MEDLINE | ID: mdl-38698241
ABSTRACT

BACKGROUND:

Systematic descriptions of anatomical damage after brachial plexus injury (BPI) at the intradural level have been scarcely reported in detail. However, considering these damages, not only in the spinal nerve roots but also in the spinal cord itself, is crucial in determining the appropriate surgical approach to restore upper limb function and address refractory pain. Therefore, the authors present a descriptive study focusing on intradural findings observed during microsurgical DREZ-lesioning.

METHODS:

This study enrolled 19 consecutive patients under the same protocol. Microsurgical observation through exposure of C4 to Th1 medullary segments allowed to describe the lesions in spinal nerve roots, meninges, and spinal cord. Electrical stimulation of the ventral roots checked the muscle responses.

RESULTS:

Extensive damage was observed among the 114 explored roots (six roots per patient), with only 21 (18.4%) ventral (VR) and 17 (14.9%) dorsal (DR) roots retaining all rootlets intact. Damage distribution varied, with the most frequent impairments in C6 VRs (18 patients) and the least in Th1 VRs (14 patients), while in all the 19 patients for the C6 DRs (the most frequently impaired) and in 14 patients for Th1 DRs (the less impaired). C4 roots were found damaged in 12 patients. Total or partial avulsions affected 63.3% and 69.8% of DRs and VRs, respectively, while 15.8% and 14.0% of the 114 DRs and VRs were atrophic, maintaining muscle responses to stimulation in half of those VRs. Pseudomeningoceles were present in 11 patients but absent in 46% of avulsed roots. Adhesive arachnoiditis was noted in 12 patients, and dorsal horn parenchymal alterations in 10.

CONCLUSIONS:

Knowledge of intradural lesions post-BPI helps in guiding surgical indications for repair and functional neurosurgery for pain control.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Raíces Nerviosas Espinales / Plexo Braquial Límite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Acta Neurochir (Wien) Año: 2024 Tipo del documento: Article País de afiliación: Grecia Pais de publicación: Austria

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Raíces Nerviosas Espinales / Plexo Braquial Límite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Acta Neurochir (Wien) Año: 2024 Tipo del documento: Article País de afiliación: Grecia Pais de publicación: Austria