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A study of antibiotic resistance pattern of clinical bacterial pathogens isolated from patients in a tertiary care hospital.
Handa, Vishal L; Patel, Bhoomi N; Bhattacharya, Dr Arpita; Kothari, Ramesh K; Kavathia, Dr Ghanshyam; Vyas, B R M.
Afiliación
  • Handa VL; Department of Biosciences, Saurashtra University, Rajkot, Gujarat, India.
  • Patel BN; Department of Biosciences, Saurashtra University, Rajkot, Gujarat, India.
  • Bhattacharya DA; Department of Microbiology, Pandit Deendayal Upadhyay Medical College, Rajkot, Gujarat, India.
  • Kothari RK; Department of Biosciences, Saurashtra University, Rajkot, Gujarat, India.
  • Kavathia DG; Department of Microbiology, Pandit Deendayal Upadhyay Medical College, Rajkot, Gujarat, India.
  • Vyas BRM; Department of Biosciences, Saurashtra University, Rajkot, Gujarat, India.
Front Microbiol ; 15: 1383989, 2024.
Article en En | MEDLINE | ID: mdl-38694800
ABSTRACT
We investigated antibiotic resistance pattern in clinical bacterial pathogens isolated from in-patients and out-patients, and compared it with non-clinical bacterial isolates. 475 bacterial strains isolated from patients were examined for antibiotic resistance. Staphylococcus spp. (148; 31.1%) were found to be the most prevalent, followed by Klebsiella pneumoniae (135; 28.4%), Escherichia coli (74; 15.5%), Pseudomonas aeruginosa (65; 13.6%), Enterobacter spp. (28; 5.8%), and Acinetobacter spp. (25; 5.2%). Drug-resistant bacteria isolated were extended spectrum-ß-lactamase K. pneumoniae (8.8%), E. coli (20%), metallo-ß-lactamase P. aeruginosa (14; 2.9%), erythromycin-inducing clindamycin resistant (7.4%), and methicillin-resistant Staphylococcus species (21.6%). Pathogens belonging to the Enterobacteriaceae family were observed to undergo directional selection developing resistance against antibiotics ciprofloxacin, piperacillin-tazobactam, cefepime, and cefuroxime. Pathogens in the surgical ward exhibited higher levels of antibiotic resistance, while non-clinical P. aeruginosa and K. pneumoniae strains were more antibiotic-susceptible. Our research assisted in identifying the drugs that can be used to control infections caused by antimicrobial resistant bacteria in the population and in monitoring the prevalence of drug-resistant bacterial pathogens.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Front Microbiol Año: 2024 Tipo del documento: Article País de afiliación: India Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Front Microbiol Año: 2024 Tipo del documento: Article País de afiliación: India Pais de publicación: Suiza