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Visible-light-induced N-alkylation of anilines with 4-hydroxybutan-2-one.
Jiang, Liya; Ni, Ling; Tang, Xinyue; Baell, Jonathan B; Huang, Fei; Ren, Lanhui.
Afiliación
  • Jiang L; School of Pharmaceutical Sciences, Nanjing Tech University Nanjing 211816 China huangfei0208@yeah.net.
  • Ni L; Institute of Zhejiang University-Quzhou 99 Zheda Road Quzhou Zhejiang Province 324000 China renlanhui@zju.edu.cn.
  • Tang X; Institute of Zhejiang University-Quzhou 99 Zheda Road Quzhou Zhejiang Province 324000 China renlanhui@zju.edu.cn.
  • Baell JB; School of Pharmaceutical Sciences, Nanjing Tech University Nanjing 211816 China huangfei0208@yeah.net.
  • Huang F; School of Pharmaceutical Sciences, Nanjing Tech University Nanjing 211816 China huangfei0208@yeah.net.
  • Ren L; Institute of Zhejiang University-Quzhou 99 Zheda Road Quzhou Zhejiang Province 324000 China renlanhui@zju.edu.cn.
RSC Adv ; 14(20): 14452-14455, 2024 Apr 25.
Article en En | MEDLINE | ID: mdl-38694550
ABSTRACT
The synthesis of amines through N-alkylation is particularly attractive. Herein, a strategy for visible-light-induced N-alkylation of anilines with 4-hydroxybutan-2-one was developed in the presence of NH4Br, which avoid the use of metals, bases and ligands. In addition, gram-scale experiments proved that the system has the potential to be scaled.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: RSC Adv Año: 2024 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: RSC Adv Año: 2024 Tipo del documento: Article Pais de publicación: Reino Unido