Your browser doesn't support javascript.
loading
Effect of a national infection control programme in Sweden on prosthetic joint infection incidence following primary total hip arthroplasty: a cohort study.
Wildeman, Peter; Rolfson, Ola; Wretenberg, Per; Nåtman, Jonatan; Gordon, Max; Söderquist, Bo; Lindgren, Viktor.
Afiliación
  • Wildeman P; Department of Orthopedics, Faculty of Medicine and Health, Orebro University, Orebro, Sweden peter.wildeman@gmail.com.
  • Rolfson O; Department of Orthopaedics, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
  • Wretenberg P; Swedish Arthroplasty Register, Registercentrum Vastra Gotaland, Gothenburg, Sweden.
  • Nåtman J; Department of Orthopedics, Faculty of Medicine and Health, Orebro University, Orebro, Sweden.
  • Gordon M; Swedish Arthroplasty Register, Registercentrum Vastra Gotaland, Gothenburg, Sweden.
  • Söderquist B; Department of Clinical Sciences, Danderyd Hospital, Karolinska Institutet, Stockholm, Sweden.
  • Lindgren V; School of Medical Sciences, Faculty of Medicine and Health, Örebro University, Orebro, Sweden.
BMJ Open ; 14(4): e076576, 2024 Apr 29.
Article en En | MEDLINE | ID: mdl-38684253
ABSTRACT

OBJECTIVES:

Prosthetic joint infection (PJI) is a serious complication following total hip arthroplasty (THA) entailing increased mortality, decreased quality of life and high healthcare costs.The primary aim was to investigate whether the national project Prosthesis Related Infections Shall be Stopped (PRISS) reduced PJI incidence after primary THA; the secondary aim was to evaluate other possible benefits of PRISS, such as shorter time to diagnosis.

DESIGN:

Cohort study.

SETTING:

In 2009, a nationwide, multidisciplinary infection control programme was launched in Sweden, PRISS, which aimed to reduce the PJI burden by 50%.

PARTICIPANTS:

We obtained data on patients undergoing primary THA from the Swedish Arthroplasty Registry 2012-2014, (n=45 723 patients, 49 946 THAs). Using personal identity numbers, this cohort was matched with the Swedish Prescribed Drug Registry. Medical records of patients with ≥4 weeks' antibiotic consumption were reviewed to verify PJI diagnosis (n=2240, 2569 THAs).

RESULTS:

The cumulative incidence of PJI following the PRISS Project was 1.2% (95% CI 1.1% to 1.3%) as compared with 0.9% (95% CI 0.8% to 1.0%) before. Cox regression models for the PJI incidence post-PRISS indicates there was no statistical significance difference versus pre-PRISS (HR 1.1 (95% CI 0.9 to 1.3)). There was similar time to PJI diagnosis after the PRISS Project 24 vs 23 days (p=0.5).

CONCLUSIONS:

Despite the comprehensive nationwide PRISS Project, Swedish PJI incidence was higher after the project and time to diagnosis remained unchanged. Factors contributing to PJI, such as increasing obesity, higher American Society of Anesthesiology class and more fractures as indications, explain the PJI increase among primary THA patients.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones Relacionadas con Prótesis / Control de Infecciones / Artroplastia de Reemplazo de Cadera Límite: Aged / Aged80 / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: BMJ Open Año: 2024 Tipo del documento: Article País de afiliación: Suecia Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones Relacionadas con Prótesis / Control de Infecciones / Artroplastia de Reemplazo de Cadera Límite: Aged / Aged80 / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: BMJ Open Año: 2024 Tipo del documento: Article País de afiliación: Suecia Pais de publicación: Reino Unido