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Elastic and Self-Healing Copolymer Coatings with Antimicrobial Function.
Laysandra, Livy; Rusli, Randy Arthur; Chen, Yu-Wei; Chen, Shi-Ju; Yeh, Yao-Wei; Tsai, Tsung-Lin; Huang, Jui-Hsiung; Chuang, Kao-Shu; Njotoprajitno, Andreas; Chiu, Yu-Cheng.
Afiliación
  • Laysandra L; Department of Chemical Engineering, National Taiwan University of Science and Technology, Taipei 10607, Taiwan.
  • Rusli RA; Department of Chemical Engineering, National Taiwan University of Science and Technology, Taipei 10607, Taiwan.
  • Chen YW; Department of Chemical Engineering, National Taiwan University of Science and Technology, Taipei 10607, Taiwan.
  • Chen SJ; Taipei Municipal Zhongshan Girls High School, Taipei 10617, Taiwan.
  • Yeh YW; Department of Biomedical Engineering, College of Engineering, National Cheng Kung University, Tainan 704, Taiwan.
  • Tsai TL; Department of Biomedical Engineering, College of Engineering, National Cheng Kung University, Tainan 704, Taiwan.
  • Huang JH; Department of Oncology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 704, Taiwan.
  • Chuang KS; Department of Green Material Technology, Green Technology Research Institute, CPC Corporation, Kaohsiung City 811, Taiwan.
  • Njotoprajitno A; Department of Green Material Technology, Green Technology Research Institute, CPC Corporation, Kaohsiung City 811, Taiwan.
  • Chiu YC; Department of Chemical Engineering, National Taiwan University of Science and Technology, Taipei 10607, Taiwan.
ACS Appl Mater Interfaces ; 16(19): 25194-25209, 2024 May 15.
Article en En | MEDLINE | ID: mdl-38684227
ABSTRACT
The revolutionary self-healing function for long-term and safe service processes has inspired researchers to implement them in various fields, including in the application of antimicrobial protective coatings. Despite the great advances that have been made in the field of fabricating self-healing and antimicrobial polymers, their poor transparency and the trade-off between the mechanical and self-healing properties limit the utility of the materials as transparent antimicrobial protective coatings for wearable optical and display devices. Considering the compatibility in the blending process, our group proposed a self-healing, self-cross-linkable poly{(n-butyl acrylate)-co-[N-(hydroxymethyl)acrylamide]} copolymer (AP)-based protective coating combined with two types of commercial cationic antimicrobial agents (i.e., dimethyl octadecyl (3-trimethoxysilylpropyl) ammonium chloride (DTSACL) and chlorhexidine gluconate (CHG)), leading to the fabrication of a multifunctional modified compound film of (AP/b%CHG)-grafted-a%DTSACL. The first highlight of this research is that the reactivity of the hydroxyl group in the N-(hydroxymethyl)acrylamide of the copolymer side chains under thermal conditions facilitates the "grafting to" process with the trimethoxysilane groups of DTSACL to form AP-grafted-DTSACL, yielding favorable thermal stability, improvement in hydrophobicity, and enhancement of mechanical strength. Second, we highlight that the addition of CHG can generate covalent and noncovalent interactions in a complex manner between the two biguanide groups of CHG with the AP and DTSACL via a thermal-triggered cross-linking reaction. The noncovalent interactions synergistically serve as diverse dynamic hydrogen bonds, leading to complete healing upon scratches and even showing over 80% self-healing efficiency on full-cut, while covalent bonding can effectively improve elasticity and mechanical strength. The soft nature of CHG also takes part in improving the self-healing of the copolymer. Moreover, it was discovered that the addition of CHG can enhance antimicrobial effectiveness, as demonstrated by the long-term superior antibacterial activity (100%) against Gram-negative (Escherichia coli) and Gram-positive (Staphylococcus aureus) bacteria and the antifouling function on a glass substrate and/or a silica wafer coated by the modified polymer.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Polímeros Idioma: En Revista: ACS Appl Mater Interfaces Asunto de la revista: BIOTECNOLOGIA / ENGENHARIA BIOMEDICA Año: 2024 Tipo del documento: Article País de afiliación: Taiwán Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Polímeros Idioma: En Revista: ACS Appl Mater Interfaces Asunto de la revista: BIOTECNOLOGIA / ENGENHARIA BIOMEDICA Año: 2024 Tipo del documento: Article País de afiliación: Taiwán Pais de publicación: Estados Unidos