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Hydroxychloroquine-Induced Phospholipidosis - A Forgotten Complication of a Common Drug.
Kothapalli, Nagamounika; Padiyar, Shivraj; Nair, Aswin M; Manikuppam, Prathyusha; Matthai, Smitha M; Roy, Sanjeet; Pulimood, Anna; Alexander, Suceena; Mathew, John.
Afiliación
  • Kothapalli N; Department of Clinical Immunology and Rheumatology, Christian Medical College, Vellore, Tamil Nadu, India.
  • Padiyar S; Department of Clinical Immunology and Rheumatology, Christian Medical College, Vellore, Tamil Nadu, India.
  • Nair AM; Department of Rheumatology, Travancore Medical College Hospital, Kollam, Kerala, India.
  • Manikuppam P; Department of Clinical Immunology and Rheumatology, Christian Medical College, Vellore, Tamil Nadu, India.
  • Matthai SM; Department of Clinical Immunology and Rheumatology, Christian Medical College, Vellore, Tamil Nadu, India.
  • Roy S; Department of Clinical Immunology and Rheumatology, Christian Medical College, Vellore, Tamil Nadu, India.
  • Pulimood A; Department of Clinical Immunology and Rheumatology, Christian Medical College, Vellore, Tamil Nadu, India.
  • Alexander S; Department of Clinical Immunology and Rheumatology, Christian Medical College, Vellore, Tamil Nadu, India.
  • Mathew J; Department of Clinical Immunology and Rheumatology, Christian Medical College, Vellore, Tamil Nadu, India.
Indian J Nephrol ; 34(2): 175-177, 2024.
Article en En | MEDLINE | ID: mdl-38681001
ABSTRACT
Hydroxychloroquine (HCQ) has immunomodulatory and immunosuppressive properties and is used in many rheumatological conditions like systemic lupus erythematosus, rheumatoid arthritis, and Sjogren's syndrome. It is usually a widely used and well-tolerated DMARD (Disease Modifying Anti Rheumatic Drugs). Its most feared toxicities include retinopathy and, rarely, cardiomyopathy. Among its other reported side effects is drug-induced phospholipidosis. Here, we report two cases of HCQ-induced phospholipidosis based on renal biopsy electron microscopy. HCQ-induced phospholipidosis, although uncommon, must be considered as one of the differentials in a patient with persistent proteinuria.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Indian J Nephrol Año: 2024 Tipo del documento: Article País de afiliación: India Pais de publicación: India
Texto completo
Añadir a Mi BVS
Imprimir
XML
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Indian J Nephrol Año: 2024 Tipo del documento: Article País de afiliación: India Pais de publicación: India