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A novel cause of erythromelalgia due to pseudoephedrine.
Kravvas, Georgios; Aboukhatwah, Nada; Ali, Lana; Bray, Adam P.
Afiliación
  • Kravvas G; Department of Dermatology University College London Hospitals NHS Foundation Trust, London, UK.
  • Aboukhatwah N; Department of Dermatology Whittington Health NHS Foundation Trust, London, UK.
  • Ali L; Department of Dermatology University Hospitals Bristol NHS Foundation Trust, Bristol, UK.
  • Bray AP; Department of Dermatology University Hospitals Bristol NHS Foundation Trust, Bristol, UK.
Oxf Med Case Reports ; 2024(4): omae037, 2024 Apr.
Article en En | MEDLINE | ID: mdl-38680776
ABSTRACT

Objective:

Erythromelalgia is a rare, highly debilitating disorder characterised by severe episodes of discomfort, erythema, and desquamation of the extremities. Its causes include genetic factors, medications, and several underlying medical conditions. This paper describes a novel cause of erythromelalgia through a case report and literature review. Case description A 47-year-old Caucasian man presented with a two-year history of intermittent pain, redness and desquamation of the hands. He experienced several such episodes, each lasting 3-4 weeks. A skin biopsy confirmed the diagnosis of erythromelalgia. After several recurrences, he admitted to the intermittent use of pseudoephedrine as a nasal decongestant, which coincided with the episodes of erythromelalgia. Complete resolution of symptoms was reported on cessation of this medication.

Conclusion:

Pseudoephedrine has been reported to cause a wide range of cutaneous reactions but has not been known to precipitate erythromelalgia. Recognition of this rare side effect may offer early diagnosis and reduced morbidity.
Palabras clave

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Oxf Med Case Reports Año: 2024 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Oxf Med Case Reports Año: 2024 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Reino Unido