Your browser doesn't support javascript.
loading
SARS-CoV-2 diagnosis in saliva samples: Usefulness and limitations.
Gutiérrez-Gómez, María-Lucía; Ruíz, Zulema; Gamboa, Fredy; Roa, Nelly S; Cardozo, Claudia; Ariza, Beatriz; Aristizábal, Andrés; Lugo, Andrés; Bolívar, Stevenson; Henao, Daniel; García-Robayo, Dabeiba-Adriana.
Afiliación
  • Gutiérrez-Gómez ML; Department of Morphological Sciences, School of Medicine, Pontificia Universidad Javeriana, Bogotá D.C, Colombia; Institute of Human Genetics, School of Medicine, Pontificia Universidad Javeriana, Bogotá D.C., Colombia. Electronic address: mlgutierrez@javeriana.edu.co.
  • Ruíz Z; Clinical Laboratory, San Ignacio University Hospital, Bogotá, D.C., Colombia.
  • Gamboa F; Center for Dental Research, School of Dentistry, Pontificia Universidad Javeriana, Bogotá D.C., Colombia; Department of Microbiology, School of Sciences, Pontificia Universidad Javeriana, Bogotá D.C., Colombia.
  • Roa NS; Center for Dental Research, School of Dentistry, Pontificia Universidad Javeriana, Bogotá D.C., Colombia; Department of Buccal System, School of Dentistry, Pontificia Universidad Javeriana, Bogotá, D.C., Colombia.
  • Cardozo C; Clinical Laboratory, San Ignacio University Hospital, Bogotá, D.C., Colombia.
  • Ariza B; Clinical Laboratory, San Ignacio University Hospital, Bogotá, D.C., Colombia.
  • Aristizábal A; Department of Nutrition and Biochemistry, School of Sciences, Pontificia Universidad Javeriana, Bogotá D.C., Colombia.
  • Lugo A; Department of Respiratory Care, respIRA group, San Ignacio University Hospital, Bogotá, D.C., Colombia.
  • Bolívar S; Department of Industrial Engineering, School of Engineering, Pontificia Universidad Javeriana, Bogotá, D. C., Colombia.
  • Henao D; Department of Dental System, School of Dentistry, Pontificia Universidad Javeriana, Bogotá, D.C., Colombia.
  • García-Robayo DA; Center for Dental Research, School of Dentistry, Pontificia Universidad Javeriana, Bogotá D.C., Colombia; Department of Buccal System, School of Dentistry, Pontificia Universidad Javeriana, Bogotá, D.C., Colombia. Electronic address: garciad@javeriana.edu.co.
Diagn Microbiol Infect Dis ; 109(3): 116320, 2024 Jul.
Article en En | MEDLINE | ID: mdl-38678688
ABSTRACT
Saliva samples are important for diagnosis, because they are noninvasive and easy to acquire. The objective of this cross-sectional study was to investigate the value saliva samples have in detecting SARS-CoV-2 in comparison to nasal swabs and a new system named CovidCheck. A standard methodology identified the virus in 185 nasopharyngeal swabs and saliva samples revealing a sensitivity, specificity and positive and negative predictive values of 82,100,100 and 94.67%, respectively for saliva samples. Viral presence in saliva samples with the standard methodology in comparison to the CovidCheck system was evaluated in 67 samples with sensitivity, specificity and positive and negative predictive values of 68, 81, 68 and 81%, respectively. In conclusion, our results highlight the usefulness saliva samples have in detecting respiratory viral infections. However, presence of viral inhibitors and viral load in saliva, and the patient's clinical status should be considered as they might affect amplifying systems results.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Saliva / Nasofaringe / Sensibilidad y Especificidad / SARS-CoV-2 / COVID-19 Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Diagn Microbiol Infect Dis Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Saliva / Nasofaringe / Sensibilidad y Especificidad / SARS-CoV-2 / COVID-19 Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Diagn Microbiol Infect Dis Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos