Hookworm genomics: dusk or dawn?
Trends Parasitol
; 40(6): 452-465, 2024 Jun.
Article
en En
| MEDLINE
| ID: mdl-38677925
ABSTRACT
Hookworms are parasites, closely related to the model nematode Caenorhabditis elegans, that are a major economic and health burden worldwide. Primarily three hookworm species (Necator americanus, Ancylostoma duodenale, and Ancylostoma ceylanicum) infect humans. Another 100 hookworm species from 19 genera infect primates, ruminants, and carnivores. Genetic data exist for only seven of these species. Genome sequences are available from only four of these species in two genera, leaving 96 others (particularly those parasitizing wildlife) without any genomic data. The most recent hookworm genomes were published 5 years ago, leaving the field in a dusk. However, assembling genomes from single hookworms may bring a new dawn. Here we summarize advances, challenges, and opportunities for studying these neglected but important parasitic nematodes.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Genómica
/
Genoma de los Helmintos
/
Infecciones por Uncinaria
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Trends Parasitol
Asunto de la revista:
PARASITOLOGIA
Año:
2024
Tipo del documento:
Article
Pais de publicación:
Reino Unido