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Exploring Blood Cell Count-Derived Ratios as Practical Diagnostic Tools for Scabies in Vulnerable Populations.
Nguyen, Hoang Thao Giang; Le, Ha Long Hai; Nguyen, Hoang Viet; Le, Huyen My; Vu, Huy Luong; Inaoka, Pleiades T; Tetsuo, Ota; Ly, Quoc Trung; Espinoza, J Luis.
Afiliación
  • Nguyen HTG; Faculty of Health Sciences, Kanazawa University, Kanazawa 920-0942, Ishikawa, Japan.
  • Le HLH; Department of Biochemistry, Hematology and Immunology, National Hospital of Dermatology and Venereology, Hanoi 100000, Vietnam.
  • Nguyen HV; Faculty of Medical Technology, Hanoi Medical University, Hanoi 116001, Vietnam.
  • Le HM; Faculty of Medical Technology, Hanoi Medical University, Hanoi 116001, Vietnam.
  • Vu HL; Department of Biochemistry, Hematology and Immunology, National Hospital of Dermatology and Venereology, Hanoi 100000, Vietnam.
  • Inaoka PT; Department of Laser and Skin Care, National Hospital of Dermatology and Venereology, Hanoi 116001, Vietnam.
  • Tetsuo O; Faculty of Health Sciences, Kanazawa University, Kanazawa 920-0942, Ishikawa, Japan.
  • Ly QT; Faculty of Health Sciences, Kanazawa University, Kanazawa 920-0942, Ishikawa, Japan.
  • Espinoza JL; Soctrang Hospital for Women and Children, Soc Trang 950000, Vietnam.
J Pers Med ; 14(4)2024 Mar 30.
Article en En | MEDLINE | ID: mdl-38673000
ABSTRACT
Scabies is a neglected tropical disease and represents a considerable global burden. Although consensus diagnostic criteria for scabies have been recently published, diagnosing scabies infestation remains challenging in clinical practice. We investigated the diagnostic utility of complete blood cell count (CBC) and CBC-derived ratios obtained at diagnosis in a set of 167 patients who are Vietnamese with confirmed scabies. These parameters were compared with those of patients with dermatophytosis (N = 800) and urticaria (N = 2023), two diseases frequent in Vietnam, which can present with similar skin manifestations to scabies and tend to pose a diagnostic challenge in vulnerable populations. Our analysis revealed that white blood cell, monocyte, and eosinophil counts were significantly higher among patients with scabies than the other two diseases. Similarly, the monocyte-to-lymphocyte ratio (MLR) and eosinophil-to-lymphocyte ratio (ELR) were significantly higher among patients with scabies. The optimal cut-off values to distinguish scabies from dermatophytosis and urticaria were 0.094 for ELR (sensitivity 74.85%, specificity 70.7%) and 0.295 for MLR (sensitivity 52.69%, specificity 73.54%). CBC, ELR, and MLR are low-cost and easily calculated parameters that may be helpful for the diagnosis of scabies.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Pers Med Año: 2024 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Pers Med Año: 2024 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Suiza