Muscle stem cell niche dynamics during muscle homeostasis and regeneration.
Curr Top Dev Biol
; 158: 151-177, 2024.
Article
en En
| MEDLINE
| ID: mdl-38670704
ABSTRACT
The process of skeletal muscle regeneration involves a coordinated interplay of specific cellular and molecular interactions within the injury site. This review provides an overview of the cellular and molecular components in regenerating skeletal muscle, focusing on how these cells or molecules in the niche regulate muscle stem cell functions. Dysfunctions of muscle stem cell-to-niche cell communications during aging and disease will also be discussed. A better understanding of how niche cells coordinate with muscle stem cells for muscle repair will greatly aid the development of therapeutic strategies for treating muscle-related disorders.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Regeneración
/
Músculo Esquelético
/
Nicho de Células Madre
/
Homeostasis
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Curr Top Dev Biol
Año:
2024
Tipo del documento:
Article
Pais de publicación:
Estados Unidos