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Risk factors and healing factors for pharyngocutaneous fistula after total laryngectomy for laryngeal cancer: An epidemiological study.
Tai, Yong; Zang, Yanzi; Liu, Tongxun; Ma, Jiqing; Qin, Litao; Ji, Yuzi; Dai, Hanqing; Wang, Guangke; Ma, Lingcao; Liu, Fei.
Afiliación
  • Tai Y; Department of Otorhinolaryngology, People's Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, China.
  • Zang Y; Department of Otorhinolaryngology, People's Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, China.
  • Liu T; Department of Otorhinolaryngology, Zhongmu County People's Hospital, Zhengzhou, China.
  • Ma J; Department of Otorhinolaryngology, People's Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, China.
  • Qin L; Henan Provincial Key Laboratory of Genetic Diseases and Functional Genomics, Henan Provincial People's Hospital, Medical Genetics Institute of Henan Province, People's Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, China.
  • Ji Y; Department of Otorhinolaryngology, People's Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, China.
  • Dai H; Department of Otorhinolaryngology, People's Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, China.
  • Wang G; Department of Otorhinolaryngology, People's Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, China.
  • Ma L; Department of Otorhinolaryngology, People's Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, China.
  • Liu F; Department of Otorhinolaryngology, People's Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, China.
Int Wound J ; 21(4): e14706, 2024 Apr.
Article en En | MEDLINE | ID: mdl-38660912
ABSTRACT
To analyse the risk factors and healing factors of pharyngocutaneous fistula (PCF) in patients with laryngeal cancer after total laryngectomy, and to explore the relevant epidemiology. A retrospective analysis was conducted on laryngeal cancer patients who underwent total laryngectomy in our hospital from January 2010 to December 2022. The 349 patients included in the study were divided into a PCF group of 79 and a non-PCF group of 270. Perform one-way analysis of variance and multivariate logistic analysis on various data of patients included in the statistics, and analyse the risk factors and healing factors of PCF. Smoking, history of radiation therapy for laryngeal cancer, history of chemotherapy for laryngeal cancer, tumour location (larynx, pharynx, oesophagus), preoperative albumin, postoperative proteinaemia, <99 haemoglobin, postoperative haemoglobin, postoperative C-reactive protein (CRP) level are the risk factors for PCF. Also, radiation therapy and postoperative proteinaemia were the main reasons for preventing PCF healing. Smoking history, laryngeal cancer, radiation therapy, albumin, haemoglobin and CRP are risk factors for postoperative PCF after total laryngectomy, while radiation therapy and postoperative hypoalbuminaemia are key factors affecting PCF healing.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Complicaciones Posoperatorias / Enfermedades Faríngeas / Neoplasias Laríngeas / Fístula Cutánea / Laringectomía Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Int Wound J Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Complicaciones Posoperatorias / Enfermedades Faríngeas / Neoplasias Laríngeas / Fístula Cutánea / Laringectomía Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Int Wound J Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido