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Alpha-emitter Peptide Receptor Radionuclide Therapy in Neuroendocrine Tumors.
Bhimaniya, Sudhir; Shah, Hina; Jacene, Heather A.
Afiliación
  • Bhimaniya S; Harvard Medical School, Department of Radiology, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA. Electronic address: sbhimaniya@bwh.harvard.edu.
  • Shah H; Harvard Medical School, Department of Radiology, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA.
  • Jacene HA; Harvard Medical School, Department of Radiology, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA.
PET Clin ; 19(3): 341-349, 2024 Jul.
Article en En | MEDLINE | ID: mdl-38658229
ABSTRACT
Peptide receptor radionuclide therapy (PRRT) has become mainstream therapy of metastatic neuroendocrine tumors not controlled by somatostatin analog therapy. Currently, beta particle-emitting radiopharmaceuticals are the mainstay of PRRT. Alpha particle-emitting radiopharmaceuticals have a theoretic advantage over beta emitters in terms of improved therapeutic efficacy due to higher cancer cell death and lower nontarget tissue radiation-induced adverse events due to shorter path length of alpha particles. We discuss the available evidence for and the role of alpha particle PRRT.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Receptores de Péptidos / Tumores Neuroendocrinos / Radiofármacos / Partículas alfa Límite: Humans Idioma: En Revista: PET Clin Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Receptores de Péptidos / Tumores Neuroendocrinos / Radiofármacos / Partículas alfa Límite: Humans Idioma: En Revista: PET Clin Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos