Laryngeal Recalibration Therapy Improves Laryngopharyngeal Symptoms in Patients With Suspected Laryngopharyngeal Reflux Disease.

Walsh, Erin; Krause, Amanda J; Greytak, Madeline; Kaizer, Alexander M; Weissbrod, Philip A; Liu, Kelli; Taft, Tiffany; Yadlapati, Rena

Walsh, Erin; Krause, Amanda J; Greytak, Madeline; Kaizer, Alexander M; Weissbrod, Philip A; Liu, Kelli; Taft, Tiffany; Yadlapati, Rena.

Afiliación

Walsh E; Department of Otolaryngology, University of California San Diego, La Jolla, California, USA.
Krause AJ; Department of Medicine, Division of Gastroenterology and Hepatology, University of California San Diego, La Jolla, California, USA.
Greytak M; Department of Medicine, Division of Gastroenterology and Hepatology, University of California San Diego, La Jolla, California, USA.
Kaizer AM; Department of Biostatistics and Informatics, Colorado School of Public Health, University of Colorado-Anschutz Medical Campus, Aurora, Colorado, USA.
Weissbrod PA; Department of Otolaryngology, University of California San Diego, La Jolla, California, USA.
Liu K; Department of Medicine, Division of Gastroenterology and Hepatology, University of California San Diego, La Jolla, California, USA.
Taft T; The Rome Foundation Research Institute, Chapel Hill, North Carolina, USA.
Yadlapati R; Department of Medicine, Division of Gastroenterology and Hepatology, University of California San Diego, La Jolla, California, USA.

Am J Gastroenterol ; 2024 May 21.

Article en En | MEDLINE | ID: mdl-38656937

ABSTRACT

ABSTRACT

INTRODUCTION:

Laryngopharyngeal symptoms such as cough, throat clearing, voice change, paradoxic vocal fold movement, or laryngospasm are hyper-responsive behaviors resulting from local irritation (e.g., refluxate) and heightened sympathetic tone. Laryngeal recalibration therapy (LRT) guided by a speech-language pathologist (SLP) provides mechanical desensitization and cognitive recalibration to suppress hyper-responsive laryngeal patterns. The aim of this study was to assess symptom response to LRT among patients with chronic laryngopharyngeal symptoms undergoing evaluation of gastroesophageal reflux disease (GERD).

METHODS:

Adults with chronic laryngopharyngeal symptoms referred for evaluation of GERD to a single center were prospectively followed. Inclusion criteria included ≥2 SLP-directed LRT sessions. Data from endoscopy, ambulatory reflux monitoring, and patient-reported outcomes were collected when available. The primary outcome was symptom response.

RESULTS:

Sixty-five participants completed LRT mean age 55.4 years (SD 17.2), 46 (71%) female, mean body mass index 25.6 kg/m 2 (6.8), and mean of 3.7 (1.9) LRT sessions. Overall, 55 participants (85%) met criteria for symptom response. Specifically, symptom response was similar between those with isolated laryngopharyngeal symptoms (13/15, 87%) and concomitant laryngopharyngeal/esophageal symptoms (42/50, 84%). Among participants who underwent reflux monitoring, symptom response was similar between those with proven, inconclusive for, and no GERD (18/21 [86%], 8/9 [89%], 10/13 [77%]).

DISCUSSION:

Eighty-five percent of patients with chronic laryngopharyngeal symptoms referred for GERD evaluation who underwent LRT-experienced laryngeal symptom response. Rates of symptom response were maintained across patients with or without proven GERD and patients with or without concomitant esophageal reflux symptoms. SLP-directed LRT is an effective approach to incorporate into multidisciplinary management of chronic laryngopharyngeal symptoms/laryngopharyngeal reflux disease.

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Am J Gastroenterol Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

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