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Transient pulmonary and gastric bleeding after iopamidol administration in a patient with marginal zone lymphoma: a case report.
Xu, Weixian; Chen, Miaozhen; Liu, Songtao; Su, Yi; Zhang, Yunhai.
Afiliación
  • Xu W; The Eighth Clinical Medical College of Guangzhou University of Chinese Medicine, 6 Qinren Road, Chancheng District, 528000, Foshan City, Guangdong Province, China.
  • Chen M; Foshan Clinical Medical School of Guangzhou University of Chinese Medicine, 3 Sanyou South Road, Chancheng District, 528000, Foshan City, Guangdong Province, China.
  • Liu S; The Eighth Clinical Medical College of Guangzhou University of Chinese Medicine, 6 Qinren Road, Chancheng District, 528000, Foshan City, Guangdong Province, China.
  • Su Y; The Eighth Clinical Medical College of Guangzhou University of Chinese Medicine, 6 Qinren Road, Chancheng District, 528000, Foshan City, Guangdong Province, China.
  • Zhang Y; The Eighth Clinical Medical College of Guangzhou University of Chinese Medicine, 6 Qinren Road, Chancheng District, 528000, Foshan City, Guangdong Province, China. fsszyyicu@163.com.
BMC Pulm Med ; 24(1): 198, 2024 Apr 22.
Article en En | MEDLINE | ID: mdl-38649880
ABSTRACT

BACKGROUND:

Iopamidol is a non-ionic, water-soluble iodine contrast agent that is considered safe for intravenous or intra-arterial administration and is widely used both in the general population and in patients undergoing oncological treatment. While adverse reactions to iopamidol have been documented, to date, no pulmonary and gastric hemorrhages induced by iopamidol have been reported in oncology patients. We report the first case of this complication. CASE PRESENTATION We report the case of a 60-year-old woman with marginal zone lymphoma who was receiving antineoplastic therapy. As part of the investigation for the condition, she underwent chest enhancement CT with iopamidol. Shortly thereafter(within five minutes), she experienced hemoptysis and hematemesis. She was intubated and admitted to the intensive care unit. Pre- and post-contrast images demonstrated the course of the hemorrhage. Flexible bronchoscopy and gastroscopy on the following day showed no active bleeding, and the patient recovered completely after antiallergy treatment. We speculate that contrast-induced hypersensitivity was the most likely cause of the transient pulmonary and gastric bleeding.

CONCLUSION:

Although rare, the complications of iopamidol, which may cause allergic reactions in the lungs and stomach, should be considered.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Yopamidol / Tomografía Computarizada por Rayos X / Linfoma de Células B de la Zona Marginal / Medios de Contraste / Hemoptisis Límite: Female / Humans / Middle aged Idioma: En Revista: BMC Pulm Med Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Yopamidol / Tomografía Computarizada por Rayos X / Linfoma de Células B de la Zona Marginal / Medios de Contraste / Hemoptisis Límite: Female / Humans / Middle aged Idioma: En Revista: BMC Pulm Med Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido