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Recent Progress of Bioinspired Cell Membrane in Cancer Immunotherapy.
Zhang, Min; Wang, Yuanhang; Song, Zhiyuan; Lu, Yimeng; Zhao, Houyu; Wang, Yihan; Lu, Ping; Liu, Yanting.
Afiliación
  • Zhang M; Department of Oncology, The First Affiliated Hospital of Xinxiang Medical University, Weihui, China.
  • Wang Y; Department of Oncology, The First Affiliated Hospital of Xinxiang Medical University, Weihui, China.
  • Song Z; Department of Ultrasound Medicine, The First Affiliated Hospital of Henan University, Kaifeng, China.
  • Lu Y; Department of Oncology, The First Affiliated Hospital of Xinxiang Medical University, Weihui, China.
  • Zhao H; Department of Oncology, The First Affiliated Hospital of Xinxiang Medical University, Weihui, China.
  • Wang Y; Department of Oncology, The First Affiliated Hospital of Xinxiang Medical University, Weihui, China.
  • Lu P; Department of Oncology, The First Affiliated Hospital of Xinxiang Medical University, Weihui, China.
  • Liu Y; Department of Oncology, The First Affiliated Hospital of Xinxiang Medical University, Weihui, China.
Clin Med Insights Oncol ; 18: 11795549241236896, 2024.
Article en En | MEDLINE | ID: mdl-38645894
ABSTRACT
By modifying immune cells, immunotherapy can activate immune response to establish long-term immune memory and prevent tumor recurrence. However, their effectiveness is largely constricted by the poor immunogenicity, immune escape, and immune tolerance of the tumor. This is related to the characteristics of the tumor itself, such as genome instability and mutation. The combination of various nanocarriers with tumor immunotherapy is beneficial for overcoming the shortcomings of traditional immunotherapy. Nanocarriers coated by cell membranes can extend blood circulation time, improve ability to evade immune clearance, and enhance targeting, thus significantly enhancing the efficacy of immunotherapy and showing great potential in tumor immunotherapy. This article reviews the application research progress of different types of cell membrane-modified nanocarriers in tumor immunotherapy, immunotherapy combination therapy, and tumor vaccines, and provides prospects for future research.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Clin Med Insights Oncol Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Clin Med Insights Oncol Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos