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[Analysis of factors leading to brain MRI lesions in Wernicke's encephalopathy].
Kuzume, Daisuke; Morimoto, Yuko; Tsutsumi, Satoshi; Yamasaki, Masahiro; Hosomi, Naohisa.
Afiliación
  • Kuzume D; Department of Neurology, Chikamori Hospital.
  • Morimoto Y; Department of Neurology, Chikamori Hospital.
  • Tsutsumi S; Department of Neurology, Chikamori Hospital.
  • Yamasaki M; Department of Neurology, Chikamori Hospital.
  • Hosomi N; Department of Neurology, Chikamori Hospital.
Rinsho Shinkeigaku ; 64(5): 361-363, 2024 May 24.
Article en Ja | MEDLINE | ID: mdl-38644211
ABSTRACT
[Objective] To investigate association between Wernicke encephalopathy (WE) and brain MRI. [Subjects] 26 patients (7 females, mean age 63.9 ± 12.7 years) with WE admitted to our department between May 2008 and September 2022. [Methods] Wernicke's encephalopathy in patients with MRI lesions was defined as "MRI-positive group" (MPG), and those without MRI lesions as "MRI-negative group" (MNG). The following parameters were assessed between the two groups age, sex, alcoholism, neurological symptoms, vitamin B1, lymphocyte, total cholesterol, albumin, and outcome at discharge. [Results] There were 17 patients in MPG. Compared to MNG, MPG had lower rates of alcohol abuse (10.0% vs 77.8%, P = 0.025), lower vitamin B1 (median 10.0 |ng/ml vs 29.0 |ng/ml, P < 0.001), and more vitamin B1 treatment dose (median 1900 |mg vs 600 |mg, P = 0.016). [Conclusion] Alcoholic WE may be overlooked if the focus is solely on brain MRI findings.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tiamina / Encefalopatía de Wernicke / Encéfalo / Imagen por Resonancia Magnética / Alcoholismo Límite: Aged / Female / Humans / Male / Middle aged Idioma: Ja Revista: Rinsho Shinkeigaku Año: 2024 Tipo del documento: Article Pais de publicación: Japón

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tiamina / Encefalopatía de Wernicke / Encéfalo / Imagen por Resonancia Magnética / Alcoholismo Límite: Aged / Female / Humans / Male / Middle aged Idioma: Ja Revista: Rinsho Shinkeigaku Año: 2024 Tipo del documento: Article Pais de publicación: Japón