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Initial experience with a novel stent-based mechanical thrombectomy device for management of acute myocardial infarction cases with large thrombus burden.
Zhi, Yuan; Madanchi, Mehdi; Cioffi, Giacomo Maria; Brunner, Julian; Stutz, Leah; Gnan, Eleonora; Gjergjizi, Varis; Attinger-Toller, Adrian; Cuculi, Florim; Bossard, Matthias.
Afiliación
  • Zhi Y; Cardiology Division, Heart Center, Luzerner Kantonsspital, 6000, Lucerne 16, Switzerland.
  • Madanchi M; Faculty of Medicine, University of Basel, Basel, Switzerland.
  • Cioffi GM; Cardiology Division, Heart Center, Luzerner Kantonsspital, 6000, Lucerne 16, Switzerland.
  • Brunner J; Faculty of Health Sciences and Medicine, University of Lucerne, Lucerne, Switzerland.
  • Stutz L; Cardiology Division, Heart Center, Luzerner Kantonsspital, 6000, Lucerne 16, Switzerland.
  • Gnan E; Faculty of Health Sciences and Medicine, University of Lucerne, Lucerne, Switzerland.
  • Gjergjizi V; Cardiology Division, Heart Center, Luzerner Kantonsspital, 6000, Lucerne 16, Switzerland.
  • Attinger-Toller A; Faculty of Medicine, University of Basel, Basel, Switzerland.
  • Cuculi F; Cardiology Division, Heart Center, Luzerner Kantonsspital, 6000, Lucerne 16, Switzerland.
  • Bossard M; Faculty of Health Sciences and Medicine, University of Lucerne, Lucerne, Switzerland.
Cardiovasc Interv Ther ; 39(3): 262-272, 2024 Jul.
Article en En | MEDLINE | ID: mdl-38642291
ABSTRACT

BACKGROUND:

Patients with acute myocardial infarction (AMI) and large thrombus burden (LTB) still represent a challenge. Afflicted patients have a high morbidity and mortality. Aspiration thrombectomy is often ineffective in those cases. Mechanical thrombectomy devices (MTDs), which are effective for management of ischemic strokes, were recently CE-approved for treatment of thrombotic coronary lesions. Real-world data about their performance in AMI cases with LTB are scarce. This study sought to summarize our early experience with a novel MTD device in this context.

METHODS:

We analyzed consecutive patients from the prospective OPTIMISER registry (NCT04988672), who have been managed with the NeVa™ MTD (Vesalio, USA) for AMI with LTB at a tertiary cardiology facility. Outcomes of interest included, among others, periprocedural complications, target lesion failure (TLF), target lesion revascularization (TLR) and target vessel myocardial infarction (TV-MI).

RESULTS:

Overall, 15 patients underwent thrombectomy with the NeVa™ device. Thrombectomy was successfully performed in 14 (93%) patients. Final TIMI 3 flow was achieved in 13 (87%) patients, while 2 (13%) patients had TIMI 2 flow. We encountered no relevant periprocedural complications, especially no stroke, stent thrombosis or vessel closure. After a mean follow-up time of 26 ± 2.9 months, 1 (7%) patient presented with TLR due to stent thrombosis (10 months after treatment with the MTD and stenting).

CONCLUSIONS:

In AMI patients with LTB, the deployment of the novel NeVa™ MTD seems efficient and safe. Further randomized trials are warranted to assess whether the use of the NeVa™ device in cases with LTB improves procedural and clinical outcomes.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Stents / Trombectomía / Infarto del Miocardio Límite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Cardiovasc Interv Ther Año: 2024 Tipo del documento: Article País de afiliación: Suiza Pais de publicación: Japón
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Stents / Trombectomía / Infarto del Miocardio Límite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Cardiovasc Interv Ther Año: 2024 Tipo del documento: Article País de afiliación: Suiza Pais de publicación: Japón