Pharmacotherapy and noninvasive neurostimulation for neuropathic pain.
Presse Med
; 53(2): 104233, 2024 Jun.
Article
en En
| MEDLINE
| ID: mdl-38636787
ABSTRACT
Neuropathic pain poses a significant challenge due to its complex mechanisms, necessitating specific treatments. In recent decades, significant progress has been made in the clinical research of neuropathic pain, marking a shift from empirical strategies to evidence-based medicine in its management. This review outlines both pharmacological and non-pharmacological interventions. Antidepressants (tricyclic and serotonin-noradrenaline reuptake inhibitors), antiepileptics (gabapentin, pregabalin), and topical agents constitute the main pharmacological treatments. These approaches target peripheral or central mechanisms associated with neuropathic pain. Noninvasive neurostimulation, including transcutaneous electrical nerve stimulation (TENS) and repetitive transcranial magnetic stimulation (rTMS), provides non-pharmacological alternatives. However, challenges persist in effectively targeting existing medications and developing drugs that act on novel targets, necessitating innovative therapeutic strategies.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Estimulación Eléctrica Transcutánea del Nervio
/
Estimulación Magnética Transcraneal
/
Neuralgia
Límite:
Humans
Idioma:
En
Revista:
Presse Med
Año:
2024
Tipo del documento:
Article
País de afiliación:
Francia
Pais de publicación:
Francia