Your browser doesn't support javascript.
loading
Molecular profiling of primary endometrioid endometrial cancer and matched lung metastases: CTNNB1 mutation as a potential driver.
Gordhandas, Sushmita; Da Cruz Paula, Arnaud; Kertowidjojo, Elizabeth C; Pareja, Fresia; Dessources, Kimberly; da Silva, Edaise M; Derakhshan, Fatemeh; Mueller, Jennifer J; Abu-Rustum, Nadeem R; Chui, M Herman; Weigelt, Britta.
Afiliación
  • Gordhandas S; Gynecology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Da Cruz Paula A; i3S Instituto de Investigação e Inovação em Saúde, Porto 4200-135, Portugal.
  • Kertowidjojo EC; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Pareja F; Department of Pathology, The University of Chicago, Chicago, IL, USA.
  • Dessources K; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • da Silva EM; Gynecology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Derakhshan F; Department of Obstetrics and Gynecology, UNC Health, Chapel Hill, NC, USA.
  • Mueller JJ; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Abu-Rustum NR; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Chui MH; Department of Pathology and Cell Biology, Columbia University, New York, NY, USA.
  • Weigelt B; Gynecology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Gynecol Oncol Rep ; 53: 101391, 2024 Jun.
Article en En | MEDLINE | ID: mdl-38633674
ABSTRACT
•Both primary endometrial cancers (ECs) and matched lung metastases shared a common ancestor with independent evolution at each site.•The two endometrioid ECs studied acquired additional mutations during the distant metastatic process.•Subclonal CTNNB1 hotspot mutations in the two primary ECs studied became clonal in the distant metastases.
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Gynecol Oncol Rep Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Países Bajos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Gynecol Oncol Rep Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Países Bajos