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60 Years of the 3Rs symposium: Lessons learned and the road ahead.
Balls, Michael; Bass, Rolf; Curren, Rodger; Fentem, Julia; Goldberg, Alan; Hartung, Thomas; Herrmann, Kathrin; Kleinstreuer, Nicole C; Libowitz, Lisa; Parascandola, John; Rowan, Andrew; Spielmann, Horst; Stephens, Martin L; Thomas, Russell S; Tsaioun, Katya.
Afiliación
  • Balls M; Faculty of Medicine and Health Sciences, University of Nottingham, Medical School, Queen's Medical Centre, Nottingham, UK.
  • Bass R; Charité - University Medicine, Berlin, Germany.
  • Curren R; Institute for In Vitro Sciences, Gaithersburg, MD, USA.
  • Fentem J; Unilever Safety and Environmental Assurance Centre (SEAC), Colworth Science Park, Bedfordshire, UK.
  • Goldberg A; Center for Alternatives to Animal Testing (CAAT), Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
  • Hartung T; Center for Alternatives to Animal Testing (CAAT), Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
  • Herrmann K; Doerenkamp-Zbinden-Chair for Evidence-based Toxicology, Baltimore, MD, USA.
  • Kleinstreuer NC; CAAT-Europe, University of Konstanz, Konstanz, Germany.
  • Libowitz L; Center for Alternatives to Animal Testing (CAAT), Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
  • Parascandola J; National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA.
  • Rowan A; Baltimore, MD, USA.
  • Spielmann H; Bethesda, MD, USA.
  • Stephens ML; Wellbeing International, Potomac, MD, USA.
  • Thomas RS; Institut für Pharmazie, Freie Universität Berlin, Berlin, Germany.
  • Tsaioun K; Center for Alternatives to Animal Testing (CAAT), Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
ALTEX ; 41(2): 179-201, 2024.
Article en En | MEDLINE | ID: mdl-38629803
ABSTRACT
When The Principles of Humane Experimental Technique was published in 1959, authors William Russell and Rex Burch had a modest goal to make researchers think about what they were doing in the laboratory ­ and to do it more humanely. Sixty years later, their groundbreaking book was celebrated for inspiring a revolution in science and launching a new field The 3Rs of alternatives to animal experimentation. On November 22, 2019, some pioneering and leading scientists and researchers in the field gathered at the Johns Hopkins Bloomberg School of Public Health in Bal­timore for the 60 Years of the 3Rs Symposium Lessons Learned and the Road Ahead. The event was sponsored by the Johns Hopkins Center for Alternatives to Animal Testing (CAAT), the Foundation for Chemistry Research and Initiatives, the Alternative Research & Development Foundation (ARDF), the American Cleaning Institute (ACI), the International Fragrance Association (IFRA), the Institute for In Vitro Sciences (IIVS), John "Jack" R. Fowle III, and the Society of Toxicology (SoT). Fourteen pres­entations shared the history behind the groundbreaking publication, international efforts to achieve its aims, stumbling blocks to progress, as well as remarkable achievements. The day was a tribute to Russell and Burch, and a testament to what is possible when people from many walks of life ­ science, government, and industry ­ work toward a common goal.
William Russell and Rex Burch published their book The Principles of Humane Experimental Technique in 1959. The book encouraged researchers to replace animal experiments where it was possible, to refine experiments with animals in order to reduce their suffering, and to reduce the number of animals that had to be used for experiments to the minimum. Sixty years later, a group of pioneering and leading scientists and researchers in the field gathered to share how the publi­cation came about and how the vision inspired international collaborations and successes on many different levels including new laws. The paper includes an overview of important milestones in the history of alternatives to animal experimentation.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Experimentación Animal / Alternativas a las Pruebas en Animales Límite: Animals Idioma: En Revista: ALTEX Asunto de la revista: MEDICINA Año: 2024 Tipo del documento: Article Pais de publicación: Alemania

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Experimentación Animal / Alternativas a las Pruebas en Animales Límite: Animals Idioma: En Revista: ALTEX Asunto de la revista: MEDICINA Año: 2024 Tipo del documento: Article Pais de publicación: Alemania