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Assessing the Combined Effects of Host and Parasite Exposure to Forever Chemicals in an Amphibian-Echinostome System.
Lech, Melissa E; Choi, Youn J; Lee, Linda S; Sepúlveda, Maria S; Hoverman, Jason T.
Afiliación
  • Lech ME; Forestry and Natural Resources, Purdue University, West Lafayette, Indiana, USA.
  • Choi YJ; Department of Agronomy, Purdue University, West Lafayette, Indiana, USA.
  • Lee LS; Department of Agronomy, Purdue University, West Lafayette, Indiana, USA.
  • Sepúlveda MS; Forestry and Natural Resources, Purdue University, West Lafayette, Indiana, USA.
  • Hoverman JT; Faculty of Life Sciences, Universidad Andres Bello, Santiago, Chile.
Environ Toxicol Chem ; 43(7): 1537-1546, 2024 Jul.
Article en En | MEDLINE | ID: mdl-38629586
ABSTRACT
Per- and polyfluoroalkyl substances (PFAS) are environmental contaminants of growing concern due to their potential negative effects on wildlife and human health. Per- and polyfluoroalkyl substances have been shown to alter immune function in various taxa, which could influence the outcomes of host-parasite interactions. To date, studies have focused on the effects of PFAS on host susceptibility to parasites, but no studies have addressed the effects of PFAS on parasites. To address this knowledge gap, we independently manipulated exposure of larval northern leopard frogs (Rana pipiens) and parasites (flatworms) via their snail intermediate host to environmentally relevant PFAS concentrations and then conducted trials to assess host susceptibility to infection, parasite infectivity, and parasite longevity after emergence from the host. We found that PFAS exposure to only the host led to no significant change in parasite load, whereas exposure of parasites to a 10-µg/L mixture of PFAS led to a significant reduction in parasite load in hosts that were not exposed to PFAS. We found that when both host and parasite were exposed to PFAS there was no difference in parasite load. In addition, we found significant differences in parasite longevity post emergence following exposure to PFAS. Although some PFAS-exposed parasites had greater longevity, this did not necessarily translate into increased infection success, possibly because of impaired movement of the parasite. Our results indicate that exposure to PFAS can potentially impact host-parasite interactions. Environ Toxicol Chem 2024;431537-1546. © 2024 SETAC.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Rana pipiens / Interacciones Huésped-Parásitos Límite: Animals Idioma: En Revista: Environ Toxicol Chem Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Rana pipiens / Interacciones Huésped-Parásitos Límite: Animals Idioma: En Revista: Environ Toxicol Chem Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos