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Inpatient outcomes for lung cancer patients presenting with superior vena cava thrombosis.
Vakil, Jay; Turk, Ekrem; Cuartas-Mesa, Maria Cristina; Deenadayalan, Vaishali; Batra, Kunnal.
Afiliación
  • Vakil J; Department of Medicine, Cook County Health, Chicago, IL, USA.
  • Turk E; Department of Medicine, Cook County Health, Chicago, IL, USA.
  • Cuartas-Mesa MC; Department of Medicine, Cook County Health, Chicago, IL, USA.
  • Deenadayalan V; Department of Medicine, Cook County Health, Chicago, IL, USA.
  • Batra K; Division of Hematology/Oncology, Cook County Health, Chicago, IL, USA.
Proc (Bayl Univ Med Cent) ; 37(3): 389-393, 2024.
Article en En | MEDLINE | ID: mdl-38628350
ABSTRACT

Background:

A specific cause of superior vena cava (SVC) syndrome, SVC thrombosis, is a rare but known complication in cancer patients. Early identification and management of SVC thrombosis in lung cancer patients may lead to improved patient outcomes and a reduction in healthcare costs.

Methods:

We studied the racial and socioeconomic differences, length of stay, total hospital charges, and all-cause mortality outcomes in patients with lung cancer with and without SVC thrombosis using data from the National Inpatient Sample. Statistical analysis was performed on STATA.

Results:

A total of 480,750 patients were hospitalized for lung cancer; 720 (0.15%) of these patients had SVC thrombosis. The lung cancer with SVC thrombosis cohort had a statistically higher proportion of Black patients. Patients with lung cancer presenting with SVC thrombosis had an increased hospital length of stay (10 vs 6 days, P < 0.001) and cost ($117,320 vs $80,806, P < 0.005) compared to those without SVC thrombosis. All-cause mortality in patients with lung cancer was 7.7% and the presence of SVC thrombosis significantly increased the odds of inpatient mortality (18.0%). Nonwhite races were associated with higher odds of mortality in lung cancer admissions.

Conclusion:

Race, insurance type, and comorbidities impacted the likelihood of developing SVC thrombosis in patients with lung cancer. SVC thrombosis is a poor prognostic factor for patients with lung cancer. Further studies to evaluate these disparities are warranted.
Palabras clave

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Proc (Bayl Univ Med Cent) Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Proc (Bayl Univ Med Cent) Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos