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Real-world data evaluating Guy's rapid diagnostic clinic as an alternate pathway for patients with FIT levels below 10.
Monroy-Iglesias, Maria Jose; Martin, Sabine; Cargaleiro, Carlos; Jones, Geraint; Steward, Lindsay; Murtagh, Colette; Bruno, Flaminia; Millwaters, Juliet; Schizas, Alexis; Watson, Harriet; Haire, Anna; Haire, Kate; Moss, Charlotte Louise; Russell, Beth; Srirajaskanthan, Raj; Van Hemelrijck, Mieke; Dolly, Saoirse.
Afiliación
  • Monroy-Iglesias MJ; Translational Oncology and Urology Research, King's College London, London, UK maria.j.monroy_iglesias@kcl.ac.uk.
  • Martin S; Medical Oncology, Guy's and St Thomas' Hospitals NHS Trust, London, UK.
  • Cargaleiro C; Medical Oncology, Guy's and St Thomas' Hospitals NHS Trust, London, UK.
  • Jones G; Medical Oncology, Guy's and St Thomas' Hospitals NHS Trust, London, UK.
  • Steward L; Southeast London Cancer Alliance, London, UK.
  • Murtagh C; Medical Oncology, Guy's and St Thomas' Hospitals NHS Trust, London, UK.
  • Bruno F; Medical Oncology, Guy's and St Thomas' Hospitals NHS Trust, London, UK.
  • Millwaters J; Medical Oncology, Guy's and St Thomas' Hospitals NHS Trust, London, UK.
  • Schizas A; Medical Oncology, Guy's and St Thomas' Hospitals NHS Trust, London, UK.
  • Watson H; Department of Colorectal Surgery, Guy's and St Thomas' NHS Foundation Trust, London, UK.
  • Haire A; Department of Colorectal Surgery, Guy's and St Thomas' NHS Foundation Trust, London, UK.
  • Haire K; Translational Oncology and Urology Research, King's College London, London, UK.
  • Moss CL; Southeast London Cancer Alliance, London, UK.
  • Russell B; Translational Oncology and Urology Research, King's College London, London, UK.
  • Srirajaskanthan R; Translational Oncology and Urology Research, King's College London, London, UK.
  • Van Hemelrijck M; Department of Gastroenterology, King's College Hospital, London, UK.
  • Dolly S; Translational Oncology and Urology Research, King's College London, London, UK.
BMJ Open ; 14(4): e080285, 2024 Apr 15.
Article en En | MEDLINE | ID: mdl-38626962
ABSTRACT

OBJECTIVE:

To analyse the effectiveness of rapid diagnostic clinics (RDCs) as an alternative pathway for patients with concerning symptoms and a faecal immunochemical test (FIT) result <10. Our primary endpoint was rate of colorectal cancer (CRC) detection. Second endpoints were rates of other cancers and gastrointestinal (GI) serious benign conditions. Finally, we analysed the specific pathway followed by FIT <10 patients with cancer at Guy's and St Thomas NHS Foundation Trust (GSTT) RDC.

DESIGN:

A retrospective and prospective cohort study.

SETTING:

GSTT RDC, one of England's largest single-centre RDCs. Sociodemographic and clinical characteristics of FIT <10 patients were analysed descriptively.

PARTICIPANTS:

Patients with an FIT result <10, seen at GSTT RDC between 1 January 2020 and 5 May 2023.

RESULTS:

A total of 1299 patients with an FIT<10 were seen at GSTT RDC between January 2020 and May 2023. Of these, 66% (n=861) reported weight loss, 62% (n=805) pain, 37% (n=481) fatigue, 34% (n=444) were anaemic and 23% (n=301) had nausea and vomiting. Among these patients, 7% (n=88) received a cancer diagnosis, 36% (n=462) were identified as having a serious benign condition. Within the patients with cancer, 9% (n=8) were diagnosed with CRC. Among patients with serious benign conditions, 7% (n=31) were referred to colorectal, hepatopancreatobiliary, or upper GI specialists.

CONCLUSION:

This study demonstrates the effectiveness of RDCs as an alternate pathway for FIT <10 patients with ongoing clinical concerns. These results contribute to enhancing patient care and optimising resource allocation within the healthcare system.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Colorrectales Límite: Humans Idioma: En Revista: BMJ Open Año: 2024 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Colorrectales Límite: Humans Idioma: En Revista: BMJ Open Año: 2024 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Reino Unido