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COVID-19 cases and their outcome among patients with uncommon co-existing illnesses: A lesson from Northern India.
Reddy, D Himanshu; Atam, Virendra; Rai, Priyanka; Khan, Farman; Pandey, Saurabh; Malhotra, Hardeep Singh; Gupta, Kamlesh Kumar; Sonkar, Satyendra Kumar; Verma, Rajeev.
Afiliación
  • Reddy DH; Department of Internal Medicine, KGMU, Lucknow, India.
  • Atam V; Department of Internal Medicine, KGMU, Lucknow, India.
  • Rai P; Department of Pathology, MVASMC, Basti, India.
  • Khan F; Department of Internal Medicine, KGMU, Lucknow, India.
  • Pandey S; Medicine & Infectious Diseases Unit, PMC Hospital, Basti, India.
  • Malhotra HS; Department of Neurology, KGMU, Lucknow, India.
  • Gupta KK; Department of Internal Medicine, KGMU, Lucknow, India.
  • Sonkar SK; Department of Internal Medicine, KGMU, Lucknow, India.
  • Verma R; Department of Internal Medicine, AIIMS, Gorakhpur, India.
Clin Epidemiol Glob Health ; 15: 101044, 2022.
Article en En | MEDLINE | ID: mdl-38620969
ABSTRACT

Introduction:

Newer coexisting conditions should be identified in order to modify newer risk factors. Aim was to identify patients with non-classical or less common coexisting conditions in patients infected of COVID 19.

Method:

Single centred study from June 2020 to May 2021 at a tertiary centre in North India. A preformed questionnaire was used to record clinical and laboratory parameters and to identify cases which are in addition to CDC list and Indian data.

Results:

0.67% (46) cases out of 6832 patients were identified to have non-classical coexisting illness. It was divided into 2 groups-infections A (60.1%) and non-infections B (39.9%). Group A included-tuberculosis- pulmonary (14.3%) & extra pulmonary (32.9%), bacterial (25.0%) viral infections [dengue, hepatitis B & C] (14.3%), HIV disease (10.7%) and malaria (3.6%). Group B included- organ transplant (27.8%), autoimmune [myasthenia gravis, polymyositis, psoriasis] (22.6%), haematologic [Haemophilia, ITP, Aplastic anaemia, APML, CML] (27.8%), uncommon malignancies [disseminated sacral chordoma and GTN] (11.1%) and snakebite (11.1%). Serum Procalcitonin was not helpful for diagnosis of bacterial infection in COVID-19 disease. Group A had significantly longer duration of illness, hepatitis and elevated CRP. The mortality in group A & B were 32.1% and 43.8% respectively. Death in non-severe COVID cases was in tetanus and snakebite. 30.7% death among tuberculosis patients. More than 70% of deaths were attributable to COVID 19 in both the groups.

Conclusion:

In Indian settings, comorbidities like tuberculosis and bacterial infections can precipitate severe COVID 19 unlike other parts of the world where tuberculosis is relatively uncommon.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Clin Epidemiol Glob Health Año: 2022 Tipo del documento: Article País de afiliación: India Pais de publicación: India
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Clin Epidemiol Glob Health Año: 2022 Tipo del documento: Article País de afiliación: India Pais de publicación: India