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Meningoradiculitis post-COVID-19 mRNA vaccination: A case report.
Landry, Alexandre; Crapoulet, Stéphanie; Boudreau, Luc H; Bourque, Christine; Weston, Lyle; Pilote, Nicholas; Desnoyers, Guillaume; Chamard-Witkowski, Ludivine.
Afiliación
  • Landry A; Centre de formation médicale du Nouveau-Brunswick, Pavillon J.-Raymond-Frenette, 50 de la Francophonie St., Moncton, NB E1A 7R1, Canada.
  • Crapoulet S; Regional Office of Research Services, Dr.-Georges-L.-Dumont University Hospital Center, Vitalité Health Network, 330 Université Ave., Moncton, NB E1C 2Z3, Canada.
  • Boudreau LH; Department of Chemistry and Biochemistry, Pavillon Léopold-Taillon, University of Moncton, 18 Antonine-Maillet Ave., Moncton, NB E1A 3E9, Canada.
  • Bourque C; Department of Infectious Disease, Dr-Georges-L.-Dumont University Hospital Center, Vitalité Health Network, 330 Université Ave., Moncton, NB E1C 2Z3, Canada.
  • Weston L; Department of Neurology, The Moncton Hospital, Horizon Health network, 135 MacBeath Ave., Moncton, NB E1C 6Z8, Canada.
  • Pilote N; Department of Radiology, Dr-Georges-L.-Dumont University Hospital Center, Vitalité Health Network, 330 Université Ave., Moncton, NB E1C 2Z3, Canada.
  • Desnoyers G; NB Diagnostic Virology Reference Center, Dr-Georges-L.-Dumont University Hospital Center, Vitalité Health Network, 330 Université Ave., Moncton, NB E1C 2Z3, Canada.
  • Chamard-Witkowski L; Centre de formation médicale du Nouveau-Brunswick, Pavillon J.-Raymond-Frenette, 50 de la Francophonie St., Moncton, NB E1A 7R1, Canada.
Clin Immunol Commun ; 2: 76-78, 2022 Dec.
Article en En | MEDLINE | ID: mdl-38620766
ABSTRACT
We present a rare case of meningoradiculitis occurring after mRNA COVID-19 vaccination. This patient, with a history of inflammatory arthritis following rubella vaccination, presented to the emergency department 4 days after her vaccination with both central and radicular nervous system symptoms. Symptoms included pain, sensory and motor deficits in L5 roots distribution, along with signs of central irritation, such as headache, difficulty concentrating and a Babinski sign. MRI showed bilateral L5 nerve roots enhancement. Lumbar puncture showed elevated protein and IgG, and relevant serologies excluded common causes. Prednisone and physical therapy helped the patient to achieve near complete recovery nine weeks after presentation. We concluded that this patient presented meningoradiculitis probably secondary to her vaccination in a context of possible overactive immune system. While such presentations might be rare, and do not constitute a general reason to abstain from vaccination, they must be well recognized and treated.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Clin Immunol Commun Año: 2022 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Clin Immunol Commun Año: 2022 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Estados Unidos