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Hemodynamics and arrhythmia disorder caused by lithium poisoning: A case report. / 锂中毒导致心律失常、血流动力学障碍1例.
Wang, Yujue; Ouyang, Lijun; Ma, Xiaoqian; Xu, Danyan; Chen, Xiaogang; He, Ying.
Afiliación
  • Wang Y; Department of Psychiatry, Second Xiangya Hospital, Central South University; National Clinical Research Center on Mental Disorders; Hunan Key Laboratory of Psychiatry and Mental Health, Changsha 410011. wangyujue0906@163.com.
  • Ouyang L; Department of Psychiatry, Second Xiangya Hospital, Central South University; National Clinical Research Center on Mental Disorders; Hunan Key Laboratory of Psychiatry and Mental Health, Changsha 410011.
  • Ma X; Department of Psychiatry, Second Xiangya Hospital, Central South University; National Clinical Research Center on Mental Disorders; Hunan Key Laboratory of Psychiatry and Mental Health, Changsha 410011.
  • Xu D; Department of Cardiovascular Medicine, Second Xiangya Hospital, Central South University, Changsha 410011, China.
  • Chen X; Department of Psychiatry, Second Xiangya Hospital, Central South University; National Clinical Research Center on Mental Disorders; Hunan Key Laboratory of Psychiatry and Mental Health, Changsha 410011.
  • He Y; Department of Psychiatry, Second Xiangya Hospital, Central South University; National Clinical Research Center on Mental Disorders; Hunan Key Laboratory of Psychiatry and Mental Health, Changsha 410011. yinghe@csu.edu.cn.
Zhong Nan Da Xue Xue Bao Yi Xue Ban ; 49(1): 153-158, 2024 Jan 28.
Article en En, Zh | MEDLINE | ID: mdl-38615177
ABSTRACT
Bipolar affective disorder refers to a category of mood disorders characterized clinically by the presence of both manic or hypomanic episodes and depressive episodes. Lithium stands out as the primary pharmacological intervention for managing bipolar affective disorder. However, its therapeutic dosage closely approaches toxic levels. Toxic symptoms appear when the blood lithium concentration surpasses 1.4 mmol/L, typically giving rise to gastrointestinal and central nervous system reactions. Cardiac toxicity is rare but serious in cases of lithium poisoning. The study reports a case of a patient with bipolar affective disorder who reached a blood lithium concentration of 6.08 mmol/L after the patient took lithium carbonate sustained-release tablets beyond the prescribed dosage daily and concurrently using other mood stabilizers. This resulted in symptoms such as arrhythmia, shock, impaired consciousness, and coarse tremors. Following symptomatic supportive treatment, including blood dialysis, the patient's physical symptoms gradually improved. It is necessary for clinicians to strengthen the prevention and recognition of lithium poisoning.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Hemodinámica / Litio Límite: Humans Idioma: En / Zh Revista: Zhong Nan Da Xue Xue Bao Yi Xue Ban Asunto de la revista: MEDICINA Año: 2024 Tipo del documento: Article Pais de publicación: China

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Hemodinámica / Litio Límite: Humans Idioma: En / Zh Revista: Zhong Nan Da Xue Xue Bao Yi Xue Ban Asunto de la revista: MEDICINA Año: 2024 Tipo del documento: Article Pais de publicación: China