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Two rare cases of benign struma ovarii with malignant recurrence.
Kantreva, Kanella; Paschou, Stavroula A; Stefanaki, Katerina; Pappa, Kanella; Kazakou, Paraskevi; Vrachnis, Dionysios; Kavoura, Evangelia; Pavlakis, Kitty; Giovannopoulou, Eirini; Lathouras, Konstantinos; Alevizaki, Maria; Saltiki, Katerina.
Afiliación
  • Kantreva K; Endocrine Unit and Diabetes Center, Department of Clinical Therapeutics, Alexandra Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
  • Paschou SA; Endocrine Unit and Diabetes Center, Department of Clinical Therapeutics, Alexandra Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
  • Stefanaki K; Endocrine Unit and Diabetes Center, Department of Clinical Therapeutics, Alexandra Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
  • Pappa K; Endocrine Unit and Diabetes Center, Department of Clinical Therapeutics, Alexandra Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
  • Kazakou P; Endocrine Unit and Diabetes Center, Department of Clinical Therapeutics, Alexandra Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
  • Vrachnis D; Endocrine Unit and Diabetes Center, Department of Clinical Therapeutics, Alexandra Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
  • Kavoura E; Pathology Department, IASO Hospital, Athens, Greece.
  • Pavlakis K; Pathology Department, IASO Hospital, Athens, Greece.
  • Giovannopoulou E; Department of Gynecological Oncology, IASO Hospital, Athens, Greece.
  • Lathouras K; Department of Gynecological Oncology, IASO Hospital, Athens, Greece.
  • Alevizaki M; Endocrine Unit and Diabetes Center, Department of Clinical Therapeutics, Alexandra Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
  • Saltiki K; Endocrine Unit and Diabetes Center, Department of Clinical Therapeutics, Alexandra Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Endocrinol Diabetes Metab Case Rep ; 2024(2)2024 Apr 01.
Article en En | MEDLINE | ID: mdl-38614119
ABSTRACT

Summary:

Struma ovarii is an ovarian teratoma that comprises 2-5% of all ovarian teratomas. Malignant transformation of struma ovarii occurs in less than 5% of all cases, and metastatic disease is even rarer. We report two cases initially diagnosed with benign struma ovarii that presented malignant transformation, specifically highly differentiated follicular carcinoma of the ovary (HDFCO), some years after the first diagnosis. Case 1 concerns a 37-year-old female featuring HDFCO of the right ovary with multiple metastatic foci, who was diagnosed with benign struma ovarii 14 years ago. Case 2 concerns a 26-year-old female diagnosed with HDFCO of the left ovary. This patient was initially diagnosed with benign struma ovarii 6 years ago that recurred 4 years after the diagnosis. Both patients were treated with surgery, adjunctive total thyroidectomy, and radioactive iodine (131I) therapy. Learning points Malignant transformation of struma ovarii is very rare (<5%). Diagnosis of HDFCO without extra ovarian dissemination is difficult due to the resemblance of its histological appearance with normal thyroid tissue. There is no consensus on the postoperative treatment of malignant struma ovarii (MSO). Clinical and histological features of MSO should be assessed for the postoperative treatment decisions. TSH suppression and thyroglobulin level measurements are necessary for patient follow-up.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Endocrinol Diabetes Metab Case Rep Año: 2024 Tipo del documento: Article País de afiliación: Grecia Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Endocrinol Diabetes Metab Case Rep Año: 2024 Tipo del documento: Article País de afiliación: Grecia Pais de publicación: Reino Unido