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Cardiovascular Magnetic Resonance Reference Ranges From the Healthy Hearts Consortium.
Raisi-Estabragh, Zahra; Szabo, Liliana; McCracken, Celeste; Bülow, Robin; Aquaro, Giovanni Donato; Andre, Florian; Le, Thu-Thao; Suchá, Dominika; Condurache, Dorina-Gabriela; Salih, Ahmed M; Chadalavada, Sucharitha; Aung, Nay; Lee, Aaron Mark; Harvey, Nicholas C; Leiner, Tim; Chin, Calvin W L; Friedrich, Matthias G; Barison, Andrea; Dörr, Marcus; Petersen, Steffen E.
Afiliación
  • Raisi-Estabragh Z; William Harvey Research Institute, NIHR Barts Biomedical Research Centre, Queen Mary University of London, Charterhouse Square, London, United Kingdom; Barts Heart Centre, St Bartholomew's Hospital, Barts Health NHS Trust, West Smithfield, London, United Kingdom.
  • Szabo L; William Harvey Research Institute, NIHR Barts Biomedical Research Centre, Queen Mary University of London, Charterhouse Square, London, United Kingdom; Barts Heart Centre, St Bartholomew's Hospital, Barts Health NHS Trust, West Smithfield, London, United Kingdom; Semmelweis University, Heart and Vas
  • McCracken C; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, National Institute for Health Research Oxford Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom.
  • Bülow R; Institute for Diagnostic Radiology and Neuroradiology, University Medicine, Ernst Moritz Arndt University Greifswald, Greifswald, Germany.
  • Aquaro GD; Academic Radiology, Department of Surgical, Medical, and Molecular Pathology and of Critical Area, University of Pisa, Pisa, Italy.
  • Andre F; Department of Cardiology, Angiology and Pneumology, University of Heidelberg, Heidelberg, Germany.
  • Le TT; National Heart Centre Singapore, Singapore; Cardiovascular Academic Clinical Programme, Duke-National University of Singapore Medical School, Singapore.
  • Suchá D; University Medical Centre Utrecht, Department of Radiology and Nuclear Medicine, Utrecht, the Netherlands.
  • Condurache DG; William Harvey Research Institute, NIHR Barts Biomedical Research Centre, Queen Mary University of London, Charterhouse Square, London, United Kingdom; Barts Heart Centre, St Bartholomew's Hospital, Barts Health NHS Trust, West Smithfield, London, United Kingdom.
  • Salih AM; William Harvey Research Institute, NIHR Barts Biomedical Research Centre, Queen Mary University of London, Charterhouse Square, London, United Kingdom; Barts Heart Centre, St Bartholomew's Hospital, Barts Health NHS Trust, West Smithfield, London, United Kingdom; Department of Computer Science, Facu
  • Chadalavada S; William Harvey Research Institute, NIHR Barts Biomedical Research Centre, Queen Mary University of London, Charterhouse Square, London, United Kingdom; Barts Heart Centre, St Bartholomew's Hospital, Barts Health NHS Trust, West Smithfield, London, United Kingdom.
  • Aung N; William Harvey Research Institute, NIHR Barts Biomedical Research Centre, Queen Mary University of London, Charterhouse Square, London, United Kingdom; Barts Heart Centre, St Bartholomew's Hospital, Barts Health NHS Trust, West Smithfield, London, United Kingdom.
  • Lee AM; William Harvey Research Institute, NIHR Barts Biomedical Research Centre, Queen Mary University of London, Charterhouse Square, London, United Kingdom.
  • Harvey NC; The Medical Research Council Lifecourse Epidemiology Centre, University of Southampton, Southampton, United Kingdom; NIHR Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom.
  • Leiner T; University Medical Centre Utrecht, Department of Radiology and Nuclear Medicine, Utrecht, the Netherlands; Mayo Clinic, Department of Radiology, Rochester, Minnesota, USA.
  • Chin CWL; National Heart Centre Singapore, Singapore; Cardiovascular Academic Clinical Programme, Duke-National University of Singapore Medical School, Singapore.
  • Friedrich MG; Department of Cardiology, Angiology and Pneumology, University of Heidelberg, Heidelberg, Germany; Department of Medicine and Diagnostic Radiology, McGill University, Montreal, Quebec, Canada.
  • Barison A; Cardiology and Cardiovascular Medicine, Fondazione Toscana Gabriele Monasterio, Pisa, Italy.
  • Dörr M; Department of Internal Medicine B, Cardiology, Pneumology, Infectious Diseases, Intensive Care Medicine, University Medicine Greifswald, Greifswald, Germany; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Germany.
  • Petersen SE; William Harvey Research Institute, NIHR Barts Biomedical Research Centre, Queen Mary University of London, Charterhouse Square, London, United Kingdom; Barts Heart Centre, St Bartholomew's Hospital, Barts Health NHS Trust, West Smithfield, London, United Kingdom; Health Data Research UK, London, Uni
JACC Cardiovasc Imaging ; 17(7): 746-762, 2024 Jul.
Article en En | MEDLINE | ID: mdl-38613554
ABSTRACT

BACKGROUND:

The absence of population-stratified cardiovascular magnetic resonance (CMR) reference ranges from large cohorts is a major shortcoming for clinical care.

OBJECTIVES:

This paper provides age-, sex-, and ethnicity-specific CMR reference ranges for atrial and ventricular metrics from the Healthy Hearts Consortium, an international collaborative comprising 9,088 CMR studies from verified healthy individuals, covering the complete adult age spectrum across both sexes, and with the highest ethnic diversity reported to date.

METHODS:

CMR studies were analyzed using certified software with batch processing capability (cvi42, version 5.14 prototype, Circle Cardiovascular Imaging) by 2 expert readers. Three segmentation methods (smooth, papillary, anatomic) were used to contour the endocardial and epicardial borders of the ventricles and atria from long- and short-axis cine series. Clinically established ventricular and atrial metrics were extracted and stratified by age, sex, and ethnicity. Variations by segmentation method, scanner vendor, and magnet strength were examined. Reference ranges are reported as 95% prediction intervals.

RESULTS:

The sample included 4,452 (49.0%) men and 4,636 (51.0%) women with average age of 61.1 ± 12.9 years (range 18-83 years). Among these, 7,424 (81.7%) were from White, 510 (5.6%) South Asian, 478 (5.3%) mixed/other, 341 (3.7%) Black, and 335 (3.7%) Chinese ethnicities. Images were acquired using 1.5-T (n = 8,779; 96.6%) and 3.0-T (n = 309; 3.4%) scanners from Siemens (n = 8,299; 91.3%), Philips (n = 498; 5.5%), and GE (n = 291, 3.2%).

CONCLUSIONS:

This work represents a resource with healthy CMR-derived volumetric reference ranges ready for clinical implementation.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Valor Predictivo de las Pruebas / Imagen por Resonancia Cinemagnética / Voluntarios Sanos Límite: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: JACC Cardiovasc Imaging Asunto de la revista: ANGIOLOGIA / CARDIOLOGIA / DIAGNOSTICO POR IMAGEM Año: 2024 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Valor Predictivo de las Pruebas / Imagen por Resonancia Cinemagnética / Voluntarios Sanos Límite: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: JACC Cardiovasc Imaging Asunto de la revista: ANGIOLOGIA / CARDIOLOGIA / DIAGNOSTICO POR IMAGEM Año: 2024 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Estados Unidos