Your browser doesn't support javascript.
loading
Microbiological Characteristics and Resistance Patterns in a Neonatal Intensive Care Unit: A Retrospective Surveillance Study.
Kasem, Sameh; Elhadidi, Ahmed; Omar, Nuralhuda; Dawoud, Tasnim; Abu Sa'da, Omar; Rahmani, Aiman; Khan, Nusrat.
Afiliación
  • Kasem S; Pediatrics and Neonatology , Tawam Hospital, Al Ain, ARE.
  • Elhadidi A; Pediatrics and Neonatology, Tawam Hospital, Al Ain, ARE.
  • Omar N; Pediatrics and Neonatology, Tawam Hospital, Al Ain, ARE.
  • Dawoud T; Pharmacy, Tawam Hospital, Al Ain, ARE.
  • Abu Sa'da O; Pediatrics and Neonatology, Tawam Hospital, Al Ain, ARE.
  • Rahmani A; Pediatrics and Neonatology, Tawam Hospital, Al Ain, ARE.
  • Khan N; Pediatrics and Neonatology, Tawam Hospital, Al Ain, ARE.
Cureus ; 16(3): e56027, 2024 Mar.
Article en En | MEDLINE | ID: mdl-38606244
ABSTRACT
BACKGROUND AND

OBJECTIVE:

This study aims to assess the prevalence and antimicrobial susceptibility patterns of bacterial infections associated with both early-onset sepsis (EOS) and late-onset sepsis (LOS).

METHODOLOGY:

This descriptive retrospective surveillance research was conducted on all neonates admitted to the neonatal ICU with bacterial sepsis, where positive cultures were isolated from sterile sites (either cerebrospinal fluid or blood) at Tawam Hospital, Al Ain, Emirate of Abu Dhabi, UAE, from January 2012 and December 2021. Antimicrobial susceptibility analysis was performed.

RESULTS:

The incidence of LOS (94.43%) was higher compared to EOS (5.56%). The most prevalent isolates (59.2%) were gram-positive bacteria, with gram-negative bacteria accounting for 40.8%. The leading isolates included coagulase-negative Staphylococci (CONS, 40.98%), Klebsiella (16.04%), Staphylococcus aureus (8.46%), Escherichia coli (8.24%), Pseudomonas (7.57%), and Group B Streptococcus (GBS, 5.12%). CONS were predominant in LOS cases (42.9%), while GBS was the main pathogen in EOS cases (44%).

CONCLUSIONS:

We observed reduced resistance levels of CONS against ampicillin, benzylpenicillin, clindamycin, erythromycin, fusidic acid, gentamicin, oxacillin, rifampicin, and trimethoprim/sulfa. S. aureus exhibited increased resistance to erythromycin, fusidic acid, gentamicin, and levofloxacin, while E. coli demonstrated decreased resistance against cephalothin, gentamicin, and trimethoprim/sulfa. The antibiotics currently employed empirically appear to provide adequate coverage against the most prevalent bacteria causing early- and late-onset neonatal infections.
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Cureus Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Cureus Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos