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Mortality and its predictors in abdominal injury across sub-Saharan Africa: systematic review and meta-analysis.
Endeshaw, Destaw; Delie, Amare Mebrat; Adal, Ousman; Tareke, Abiyu Abadi; Bogale, Eyob Ketema; Anagaw, Tadele Fentabel; Tiruneh, Misganaw Guadie; Fenta, Eneyew Talie.
Afiliación
  • Endeshaw D; Department of Adult Health Nursing, School of Health Science, College of Medicine and Health Science, Bahir Dar University, Bahir Dar, Ethiopia. destawendeshaw@gmail.com.
  • Delie AM; Department of Public Health, College of medicine and health science, Injibara University, Injibara, Ethiopia.
  • Adal O; Department of emergency and critical care nursing, School of Health Science, College of Medicine and Health Science, Bahir Dar University, Bahir Dar, Ethiopia.
  • Tareke AA; Amref Health in Africa, COVID-19 vaccine/EPI technical assistant at West Gondar zonal health department, Gondar, Ethiopia.
  • Bogale EK; Health Promotion and Behavioral science department, College of medicine and health science, Bahir Dar University, Bahir Dar, Ethiopia.
  • Anagaw TF; Health Promotion and Behavioral science department, College of medicine and health science, Bahir Dar University, Bahir Dar, Ethiopia.
  • Tiruneh MG; Department of Health Systems and Policy, Institute of Public Health, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
  • Fenta ET; Department of Public Health, College of medicine and health science, Injibara University, Injibara, Ethiopia.
BMC Emerg Med ; 24(1): 57, 2024 Apr 11.
Article en En | MEDLINE | ID: mdl-38605305
ABSTRACT

BACKGROUND:

Abdominal injuries exert a significant impact on global morbidity and mortality. The aggregation of mortality data and its determinants across different regions holds immense importance for designing informed healthcare strategies. Hence, this study assessed the pooled mortality rate and its predictors across sub-Saharan Africa.

METHOD:

This meta-analysis employed a comprehensive search across multiple electronic databases including PubMed, Africa Index Medicus, Science Direct, and Hinari, complemented by a search of Google Scholar. Subsequently, data were extracted into an Excel format. The compiled dataset was then exported to STATA 17 statistical software for analysis. Utilizing the Dersimonian-Laird method, a random-effect model was employed to estimate the pooled mortality rate and its associated predictors. Heterogeneity was evaluated via the I2 test, while publication bias was assessed using a funnel plot along with Egger's, and Begg's tests.

RESULT:

This meta-analysis, which includes 33 full-text studies, revealed a pooled mortality rate of 9.67% (95% CI; 7.81, 11.52) in patients with abdominal injuries across sub-Saharan Africa with substantial heterogeneity (I2 = 87.21%). This review also identified significant predictors of mortality. As a result, the presence of shock upon presentation demonstrated 6.19 times (95% CI; 3.70-10.38) higher odds of mortality, followed by ICU admission (AOR 5.20, 95% CI; 2.38-11.38), blunt abdominal injury (AOR 8.18, 95% CI; 4.97-13.45), post-operative complications (AOR 8.17, 95% CI; 4.97-13.44), and the performance of damage control surgery (AOR 4.62, 95% CI; 1.85-11.52).

CONCLUSION:

Abdominal injury mortality is notably high in sub-Saharan Africa. Shock at presentation, ICU admission, blunt abdominal injury, postoperative complications, and use of damage control surgery predict mortality. Tailored strategies to address these predictors could significantly reduce deaths in the region.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Traumatismos Abdominales Límite: Humans País/Región como asunto: Africa Idioma: En Revista: BMC Emerg Med Asunto de la revista: MEDICINA DE EMERGENCIA Año: 2024 Tipo del documento: Article País de afiliación: Etiopia Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Traumatismos Abdominales Límite: Humans País/Región como asunto: Africa Idioma: En Revista: BMC Emerg Med Asunto de la revista: MEDICINA DE EMERGENCIA Año: 2024 Tipo del documento: Article País de afiliación: Etiopia Pais de publicación: Reino Unido