Your browser doesn't support javascript.
loading
Sitting knee-flexion angle does not influence endothelial-dependent vasodilation in laboratory or free-living conditions.
Shivgulam, Madeline E; O'Brien, Myles W; Wu, Yanlin; Liu, Haoxuan; Petterson, Jennifer L; Schwartz, Beverly D; Kimmerly, Derek S.
Afiliación
  • Shivgulam ME; Geriatric Medicine Research, Nova Scotia Health, Halifax, NS, Canada.
  • O'Brien MW; Department of Medicine, Université de Sherbrooke, Sherbrooke, QC, Canada.
  • Wu Y; Centre de Formation Médicale Du Nouveau-Brunswick, Université de Sherbrooke, Moncton, NB, Canada.
  • Liu H; Autonomic Cardiovascular Control and Exercise Laboratory, Division of Kinesiology, School of Health and Human Performance, Faculty of Health, Dalhousie University, Halifax, NS, Canada.
  • Petterson JL; Autonomic Cardiovascular Control and Exercise Laboratory, Division of Kinesiology, School of Health and Human Performance, Faculty of Health, Dalhousie University, Halifax, NS, Canada.
  • Schwartz BD; Autonomic Cardiovascular Control and Exercise Laboratory, Division of Kinesiology, School of Health and Human Performance, Faculty of Health, Dalhousie University, Halifax, NS, Canada.
  • Kimmerly DS; Autonomic Cardiovascular Control and Exercise Laboratory, Division of Kinesiology, School of Health and Human Performance, Faculty of Health, Dalhousie University, Halifax, NS, Canada.
Vasc Med ; 29(4): 381-389, 2024 Aug.
Article en En | MEDLINE | ID: mdl-38594895
ABSTRACT

INTRODUCTION:

Single bouts of prolonged bent-legged sitting attenuate popliteal endothelial-dependent vasodilation (as assessed via flow-mediated dilation [FMD]), which is partially attributed to arterial 'kinking'. However, the impact of knee-flexion angle on sitting-induced popliteal FMD is unknown. The objective of this study was to perform separate laboratory and free-living studies to test the hypotheses that (1) popliteal FMD impairments would be graded between knee flexions at 90° (bent-legged sitting) > 45° > 0° (straight-legged sitting) following a 3-hour bout of sitting; and (2) more habitual time spent bent-legged sitting (< 45°) would be associated with lower FMD.

METHODS:

The laboratory study included eight young, healthy adults (24 ± 2 years; four women) who underwent two sitting bouts over 2 days with one leg positioned at a knee-flexion angle of 0° or 90° and the opposite leg at 45° knee flexion. Popliteal FMD was assessed at pre- and postsitting timepoints.

RESULTS:

Sitting-induced reductions in FMD were similar between all knee-flexion angles (all, p > 0.674). The free-living study included 35 young, healthy adults (23 ± 3 years; 16 women) who wore three activPAL monitors (torso, thigh, shin) to determine detailed sedentary postures. Time spent sedentary (624 ± 127 min/day), straight-legged sitting (112 ± 98 min/day), and bent-legged sitting (442 ± 106 min/day) were not related to relative FMD (5.3 ± 1.8%; all, p > 0.240).

CONCLUSION:

These findings suggest that knee-flexion angle-mediated arterial 'kinking' during sitting is not a major contributor toward sitting-induced popliteal endothelial-dependent vasodilatory dysfunction.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Arteria Poplítea / Vasodilatación / Voluntarios Sanos / Sedestación / Articulación de la Rodilla Límite: Adult / Female / Humans / Male Idioma: En Revista: Vasc Med Asunto de la revista: ANGIOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Arteria Poplítea / Vasodilatación / Voluntarios Sanos / Sedestación / Articulación de la Rodilla Límite: Adult / Female / Humans / Male Idioma: En Revista: Vasc Med Asunto de la revista: ANGIOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Reino Unido