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Outcomes of primary repair of cleft palate using sommerled intravelar veloplasty associated with velocardiofacial syndrome.
Esmailzade Moghimi, Sarah; Rezaei, Parisa; Sadeghi, Saba; Feizi, Awat; Derakhshandeh, Fatemeh.
Afiliación
  • Esmailzade Moghimi S; Faculty of Rehabilitation Sciences, Isfahan University of Medical Sciences, Isfahan, Iran; Faculty of Rehabilitation Sciences, Tehran University of Medical Sciences, Tehran, Iran.
  • Rezaei P; Department of Speech and Language Pathology, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, Iran.
  • Sadeghi S; School of Rehabilitation Sciences, Faculty of Health Sciences, University of Ottawa, Ottawa, Ontario, Canada.
  • Feizi A; Department of Biostatistics, Faculty of Nutrition and Food Sciences, Isfahan University of Medical Sciences, Isfahan, Iran.
  • Derakhshandeh F; Craniofacial and Cleft Research Center, Isfahan University of Medical Sciences, Isfahan, Iran. Electronic address: derakhshandeh@rehab.mui.ac.ir.
Int J Pediatr Otorhinolaryngol ; 179: 111940, 2024 Apr.
Article en En | MEDLINE | ID: mdl-38588634
ABSTRACT

OBJECTIVES:

Velocardiofacial syndrome, a prevalent microdeletion syndrome occurring in 1 in 2000-4000 live births, is marked by speech and language disorders, notably velopharyngeal dysfunction. This study investigates speech outcomes, nasometric and videofluoroscopic results before and after primary repair of cleft palate using the Sommerlad intravelar veloplasty (SIVV) technique within the Isfahan cleft care team for patients with velocardiofacial syndrome.

METHODS:

Employing a quasi-experimental design, 19 participants with velocardiofacial syndrome, who underwent primary cleft palate repair by the Isfahan cleft care team, were included through convenience sampling. Perceptual and instrumental outcomes were assessed pre-and post-operatively. Statistical analysis encompassed paired t-tests and the non-parametric Wilcoxon signed-rank test (p < 0.05).

RESULTS:

The study identified no statistically significant differences between pre-and post-surgical speech outcome parameters and nasalance scores. Nonetheless, a significant distinction emerged in the velopharyngeal closure ratio based on fluoroscopic evaluation (p = 0.038).

CONCLUSION:

The efficacy of the SIVV technique in treating velopharyngeal dysfunction in velocardiofacial syndrome patients is inconclusive, demanding further research. Post-surgical speech outcomes are influenced by surgical technique, hypotonia, apraxia of speech, and surgery timing. Notably, an elevated velopharyngeal valve closure ratio, though anatomically indicative, does not exclusively predict surgical success.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Insuficiencia Velofaríngea / Fisura del Paladar / Procedimientos de Cirugía Plástica / Síndrome de DiGeorge Límite: Humans Idioma: En Revista: Int J Pediatr Otorhinolaryngol Año: 2024 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Irlanda

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Insuficiencia Velofaríngea / Fisura del Paladar / Procedimientos de Cirugía Plástica / Síndrome de DiGeorge Límite: Humans Idioma: En Revista: Int J Pediatr Otorhinolaryngol Año: 2024 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Irlanda