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A controversial question: Can morphometry and clinical history be enough to diagnose hippocampal dysplasia?
Arruda, Ianne Lucena; Arruda, Rivus Ferreira; da Silveira, Rayanne Maria Brandão; Duarte, Jeana Torres Corso; Guaranha, Mirian Salvadori Bittar; Guilhoto, Laura Maria; Carrete Júnior, Henrique; Stavale, Joao Norberto; Centeno, Ricardo Silva; Yacubian, Elza Marcia Targas; Peixoto-Santos, Jose Eduardo.
Afiliación
  • Arruda IL; Epilepsy Research and Treatment Unit, Department of Neurology and Neurosurgery, Federal University of São Paulo (Unifesp), São Paulo, Brazil.
  • Arruda RF; Neuroscience Sector, Department of Neurology and Neurosurgery, Federal University of São Paulo (UNIFESP), São Paulo, Brazil.
  • da Silveira RMB; Epilepsy Research and Treatment Unit, Department of Neurology and Neurosurgery, Federal University of São Paulo (Unifesp), São Paulo, Brazil.
  • Duarte JTC; Neuroscience Sector, Department of Neurology and Neurosurgery, Federal University of São Paulo (UNIFESP), São Paulo, Brazil.
  • Guaranha MSB; Epilepsy Research and Treatment Unit, Department of Neurology and Neurosurgery, Federal University of São Paulo (Unifesp), São Paulo, Brazil.
  • Guilhoto LM; Epilepsy Research and Treatment Unit, Department of Neurology and Neurosurgery, Federal University of São Paulo (Unifesp), São Paulo, Brazil.
  • Carrete Júnior H; Epilepsy Research and Treatment Unit, Department of Neurology and Neurosurgery, Federal University of São Paulo (Unifesp), São Paulo, Brazil.
  • Stavale JN; Epilepsy Research and Treatment Unit, Department of Neurology and Neurosurgery, Federal University of São Paulo (Unifesp), São Paulo, Brazil.
  • Centeno RS; Diagnostic Imaging Sector, Department of Diagnostic Imaging, Federal University of São Paulo (Unifesp), São Paulo, Brazil.
  • Yacubian EMT; Department of Pathology, Federal University of São Paulo (Unifesp), São Paulo, Brazil.
  • Peixoto-Santos JE; Neurosurgery Sector, Department of Neurology and Neurosurgery, Federal University of São Paulo (Unifesp), São Paulo, Brazil.
Epileptic Disord ; 26(3): 382-391, 2024 Jun.
Article en En | MEDLINE | ID: mdl-38588048
ABSTRACT
The presence of dysmorphic neurons with strong cytoplasmatic accumulation of heavy non-phosphorylated neurofilament is crucial for the diagnostics of focal cortical dysplasia type II (FCDII). While ILAE's classification describes neocortical dysplasias, some groups have reported patients with mesial t abnormal neurons in the hippocampus of mesial temporal lobe epilepsy. Here we report a patient with such abnormal neurons in the hippocampus and compared it with previous reports of hippocampal dysplasia. Finally, we discuss the need for diagnostic criteria of hippocampal dysplasia.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Epilepsia del Lóbulo Temporal / Hipocampo Límite: Adult / Humans Idioma: En Revista: Epileptic Disord Asunto de la revista: CEREBRO / NEUROLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Epilepsia del Lóbulo Temporal / Hipocampo Límite: Adult / Humans Idioma: En Revista: Epileptic Disord Asunto de la revista: CEREBRO / NEUROLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Estados Unidos