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Guidelines for Pathologic Diagnosis of Mesothelioma.
Husain, Aliya N; Chapel, David B; Attanoos, Richard; Beasley, Mary Beth; Brcic, Luka; Butnor, Kelly; Chirieac, Lucian R; Churg, Andrew; Dacic, Sanja; Galateau-Salle, Francoise; Hiroshima, Kenzo; Hung, Yin P; Klebe, Sonja; Krausz, Thomas; Khoor, Andras; Litzky, Leslie; Marchevsky, Alberto; Nabeshima, Kazuki; Nicholson, Andrew G; Pavlisko, Elizabeth N; Roden, Anja C; Roggli, Victor; Sauter, Jennifer L; Schulte, Jefree J; Sheaff, Michael; Travis, William D; Tsao, Ming-Sound; Walts, Ann E; Colby, Thomas V.
Afiliación
  • Husain AN; From the Department of Pathology, University of Chicago, Chicago, Illinois (Husain, Krausz).
  • Chapel DB; The Department of Pathology, University of Michigan, Ann Arbor (Chapel).
  • Attanoos R; The Department of Cellular Pathology and School of Medicine, University Hospital of Wales and Cardiff University, Cardiff, United Kingdom (Attanoos).
  • Beasley MB; The Department of Pathology, Mount Sinai Hospital, New York, New York (Beasley).
  • Brcic L; The Department Diagnostic and Research Institute of Pathology Medical University of Graz, Graz, Austria (Brcic).
  • Butnor K; The Department of Pathology & Laboratory Medicine, University of Vermont College of Medicine, Burlington (Butnor).
  • Chirieac LR; The Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts (Chirieac).
  • Churg A; The Department of Pathology, University of British Columbia, Vancouver, British Columbia, Canada (Churg).
  • Dacic S; The Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania (Dacic).
  • Galateau-Salle F; Laboratoire d'Anatomie Pathologique, Caen-Cedex, France (Galateau-Salle).
  • Hiroshima K; The Department of Biochemistry and Genetics, Chiba University Graduate School of Medicine, Chiba, Japan (Hiroshima).
  • Hung YP; The Department of Pathology, Massachusetts General Hospital, Boston (Hung).
  • Klebe S; The Department of Anatomical Pathology, SA Pathology and Flinders University, Bedford Park SA, Australia (Klebe).
  • Krausz T; From the Department of Pathology, University of Chicago, Chicago, Illinois (Husain, Krausz).
  • Khoor A; The Department of Laboratory Medicine and Pathology, Mayo Clinic, Jacksonville, Florida (Khoor).
  • Litzky L; The Department of Pathology and Laboratory Medicine, University of Pennsylvania Medical Center, Philadelphia (Litzky).
  • Marchevsky A; The Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, California (Marchevsky, Walts).
  • Nabeshima K; The Department of Clinical Pathology, Fukuoka Tokushukai Hospital, Kasuga City, Fukuoka Prefecture, Japan (Nabeshima).
  • Nicholson AG; The Department of Histopathology, Royal Brompton and Harefield NHS Foundation Trust, London, United Kingdom (Nicholson).
  • Pavlisko EN; The Department of Pathology, Duke University Medical Center, Durham, North Carolina (Pavlisko, Roggli).
  • Roden AC; The Department of Pathology and Laboratory Medicine, Mayo Clinic, Rochester, Minnesota (Roden).
  • Roggli V; The Department of Pathology, Duke University Medical Center, Durham, North Carolina (Pavlisko, Roggli).
  • Sauter JL; The Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, New York (Sauter, Travis).
  • Schulte JJ; The Department of Pathology and Laboratory Medicine, University of Wisconsin, Madison (Schulte).
  • Sheaff M; The Department of Cellular Pathology, Barts Health NHS Trust, London, United Kingdom (Sheaff).
  • Travis WD; The Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, New York (Sauter, Travis).
  • Tsao MS; The Department of Laboratory Medicine and Pathobiology, University of Health Network and University of Toronto, Toronto, Ontario, Canada (Tsao).
  • Walts AE; The Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, California (Marchevsky, Walts).
  • Colby TV; Laboratory Medicine and Pathology, Mayo Clinic Arizona, Scottsdale (Emeritus) (Colby).
Arch Pathol Lab Med ; 2024 Apr 08.
Article en En | MEDLINE | ID: mdl-38586983
ABSTRACT
CONTEXT.­ Mesothelioma is an uncommon tumor that can be difficult to diagnose. OBJECTIVE.­ To provide updated, practical guidelines for the pathologic diagnosis of mesothelioma. DATA SOURCESPathologists involved in the International Mesothelioma Interest Group and others with expertise in mesothelioma contributed to this update. Reference material includes peer-reviewed publications and textbooks. CONCLUSIONS.­ There was consensus opinion regarding guidelines for (1) histomorphologic diagnosis of mesothelial tumors, including distinction of epithelioid, biphasic, and sarcomatoid mesothelioma; recognition of morphologic variants and patterns; and recognition of common morphologic pitfalls; (2) molecular pathogenesis of mesothelioma; (3) application of immunohistochemical markers to establish mesothelial lineage and distinguish mesothelioma from common morphologic differentials; (4) application of ancillary studies to distinguish benign from malignant mesothelial proliferations, including BAP1 and MTAP immunostains; novel immunomarkers such as Merlin and p53; fluorescence in situ hybridization (FISH) for homozygous deletion of CDKN2A; and novel molecular assays; (5) practical recommendations for routine reporting of mesothelioma, including grading epithelioid mesothelioma and other prognostic parameters; (6) diagnosis of mesothelioma in situ; (7) cytologic diagnosis of mesothelioma, including use of immunostains and molecular assays; and (8) features of nonmalignant peritoneal mesothelial lesions.

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Arch Pathol Lab Med Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Arch Pathol Lab Med Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos