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Relationship between maternal arterial and foetal cord carbon dioxide tension and neonatal outcome in critically ill pregnant women at delivery.
Scharf, Katelyn T; Bharadwaj, Shobana; Lankford, Allison; Wong, Michael; Kodali, Bhavani S.
Afiliación
  • Scharf KT; Department of Anesthesiology, University of Maryland School of Medicine, Baltimore, MD, United States.
  • Bharadwaj S; Department of Anesthesiology, University of Maryland School of Medicine, Baltimore, MD, United States.
  • Lankford A; Department of Obstetrics and Gynecology, University of Maryland School of Medicine, Baltimore, MD, United States.
  • Wong M; Department of Anesthesiology, University of Maryland School of Medicine, Baltimore, MD, United States.
  • Kodali BS; Department of Anesthesiology, University of Maryland School of Medicine, Baltimore, MD, United States.
Indian J Anaesth ; 68(4): 354-359, 2024 Apr.
Article en En | MEDLINE | ID: mdl-38586257
ABSTRACT
Background and

Aims:

No studies have evaluated the relationship between maternal arterial partial pressure of carbon dioxide (mPaCO2) and umbilical cord venous partial pressure of carbon dioxide (PCO2) in critically ill pregnant women at delivery. Based on the studies in healthy pregnant women, an mPaCO2 target of ≤50 mmHg is a suggested threshold during mechanical ventilation in critically ill parturients. We evaluated the relationship between mPaCO2 and neonatal cord gases in critically ill parturients at delivery as the primary objective. The relationship between mPaCO2 and APGAR scores at delivery was also analysed as a secondary objective.

Methods:

Maternal and neonatal cord gas data at delivery and APGAR scores were obtained by a retrospective chart review of 25 consecutive parturients with severe respiratory compromise who were delivered during mechanical ventilation. Linear regression was used to assess the relationship between mPaCO2 and umbilical artery and vein PCO2 and between mPaCO2 and APGAR scores at 1 and 5 min.

Results:

There was a positive correlation between mPaCO2 and neonatal cord venous PCO2 (P = 0.013). Foetal venous PCO2 exceeded predelivery mPaCO2 by 17.5 (7.5) mmHg. There was an inverse relationship between mPaCO2 and neonatal APGAR scores at 1 and 5 min (P = 0.006 and P = 0.007, respectively).

Conclusion:

Foetal cord venous PCO2 can be predicted if mPaCO2 values are known. Unlike in healthy pregnant women, there was an inverse relationship between rising mPaCO2 levels and neonatal APGAR scores in critically ill pregnant women who had several associated compounding factors.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Indian J Anaesth Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: India
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Indian J Anaesth Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: India