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Non-scheduled short-acting opioid to taper off opioids?
Liu, Renyu; Milas, Bonnie; Grothusen, John.
Afiliación
  • Liu R; Department of Anesthesiology and Critical Care, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Milas B; Department of Neurology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Grothusen J; Department of Anesthesiology and Critical Care, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
CNS Neurosci Ther ; 30(4): e14705, 2024 04.
Article en En | MEDLINE | ID: mdl-38584343
ABSTRACT
This commentary discusses the issues related to the current pharmacotherapy using super long-acting opioids (for the potential convenience for both patients and medical providers) for opioid addiction and argues for the potential to use a non-scheduled short-acting opioid to taper off opioids to reduce total number of patients on opioids and ultimately reduce opioid-related death. This article also proposes to develop short-acting opioids for addiction management instead of the current long-acting regimen. The authors further suggest that dezocine, a previously FDA approved medication for perioperative pain management and a non-scheduled opioid, be brought back to clinical practice in the US as a potential alternative addiction management medication, especially for those who are highly motivated to quit opioids completely using a taper off strategy.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Analgésicos Opioides / Trastornos Relacionados con Opioides Límite: Humans Idioma: En Revista: CNS Neurosci Ther Asunto de la revista: NEUROLOGIA / TERAPEUTICA Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Analgésicos Opioides / Trastornos Relacionados con Opioides Límite: Humans Idioma: En Revista: CNS Neurosci Ther Asunto de la revista: NEUROLOGIA / TERAPEUTICA Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido