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A metal-organic framework signaling probe-mediated immunosensor for the economical and rapid determination of enrofloxacin in milk.
Dong, Yiming; Zhang, Yu; Liu, Puyue; Zhu, Shiyi; Peng, Xuewen; Hu, Xiaobo; Zhang, Xiya; Chen, Yiping.
Afiliación
  • Dong Y; College of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070, Hubei, China.
  • Zhang Y; College of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070, Hubei, China.
  • Liu P; College of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070, Hubei, China.
  • Zhu S; College of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070, Hubei, China.
  • Peng X; College of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070, Hubei, China.
  • Hu X; College of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070, Hubei, China.
  • Zhang X; College of Food Science and Technology, Henan Agricultural University, Zhengzhou 450046, Henan, China.
  • Chen Y; College of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070, Hubei, China; Academy of Food Interdisciplinary Science, School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, Liaoning, China. Electronic address: chenyiping@mail.hzau.edu.cn.
Food Chem ; 449: 139050, 2024 Aug 15.
Article en En | MEDLINE | ID: mdl-38581779
ABSTRACT
Ensuring the safety of animal-derived foods requires the reliable and swift identification of enrofloxacin residues to monitor the presence of antibiotics. In this regard, we synthesized, tuned, and investigated the optical properties of a bimetallic metal-organic framework (Ce/Zr-UiO 66). The investigation was facilitated by employing a polydopamine-coated pipette tip with high adsorption efficiency, serving as an immunoreactive carrier. Subsequently, an immunofunctionalized variant of Ce/Zr-UiO 66, referred to as Ce/Zr-UiO 66@ Bovine serum albumin-enrofloxacin, was developed as an optical probe for the rapid and sensitive identification of enrofloxacin across a variety of samples. The method can accurately detect enrofloxacin at concentrations as low as 0.12 ng/mL, with a determination time of under 15 min; furthermore, it demonstrates exceptional efficacy when applied to food, environmental, and clinical samples. The implementation of this methodology offers a valuable means for cost-effective, rapid, and on-site enrofloxacin determination.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Contaminación de Alimentos / Leche / Estructuras Metalorgánicas / Enrofloxacina / Antibacterianos Límite: Animals Idioma: En Revista: Food Chem Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Contaminación de Alimentos / Leche / Estructuras Metalorgánicas / Enrofloxacina / Antibacterianos Límite: Animals Idioma: En Revista: Food Chem Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido