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FERONIA-mediated TIR1/AFB2 oxidation stimulates auxin signaling in Arabidopsis.
Lu, Baiyan; Wang, Shengnan; Feng, Hanqian; Wang, Jing; Zhang, Kaixing; Li, Yilin; Wu, Ping; Zhang, Minmin; Xia, Yanshu; Peng, Chao; Li, Chao.
Afiliación
  • Lu B; School of Life Sciences, East China Normal University, Shanghai 200241, China.
  • Wang S; School of Life Sciences, East China Normal University, Shanghai 200241, China.
  • Feng H; School of Life Sciences, East China Normal University, Shanghai 200241, China.
  • Wang J; School of Life Sciences, East China Normal University, Shanghai 200241, China.
  • Zhang K; School of Life Sciences, East China Normal University, Shanghai 200241, China.
  • Li Y; National Facility for Protein Science Shanghai, Zhangjiang Lab, Shanghai Advanced Research Institute, Chinese Academy of Sciences, Shanghai 201210, China.
  • Wu P; National Facility for Protein Science Shanghai, Zhangjiang Lab, Shanghai Advanced Research Institute, Chinese Academy of Sciences, Shanghai 201210, China.
  • Zhang M; School of Life Sciences, East China Normal University, Shanghai 200241, China.
  • Xia Y; School of Life Sciences, East China Normal University, Shanghai 200241, China.
  • Peng C; National Facility for Protein Science Shanghai, Zhangjiang Lab, Shanghai Advanced Research Institute, Chinese Academy of Sciences, Shanghai 201210, China.
  • Li C; School of Life Sciences, East China Normal University, Shanghai 200241, China. Electronic address: cli@bio.ecnu.edu.cn.
Mol Plant ; 17(5): 772-787, 2024 May 06.
Article en En | MEDLINE | ID: mdl-38581129
ABSTRACT
The phytohormone auxin plays a pivotal role in governing plant growth and development. Although the TRANSPORT INHIBITOR RESPONSE1/AUXIN SIGNALING F-BOX (TIR1/AFB) receptors function in both the nucleus and cytoplasm, the mechanism governing the distribution of TIR1/AFBs between these cellular compartments remains unknown. In this study, we demonstrate that auxin-mediated oxidation of TIR1/AFB2 is essential for their targeting to the nucleus. We showed that small active molecules, reactive oxygen species (ROS) and nitric oxide (NO), are indispensable for the nucleo-cytoplasmic distribution of TIR1/AFB2 in trichoblasts and root hairs. Further studies revealed that this process is regulated by the FERONIA receptor kinase-NADPH oxidase signaling pathway. Interestingly, ROS and NO initiate oxidative modifications in TIR1C140/516 and AFB2C135/511, facilitating their subsequent nuclear import. The oxidized forms of TIR1C140/516 and AFB2C135/511 play a crucial role in enhancing the function of TIR1 and AFB2 in transcriptional auxin responses. Collectively, our study reveals a novel mechanism by which auxin stimulates the transport of TIR1/AFB2 from the cytoplasm to the nucleus, orchestrated by the FERONIA-ROS signaling pathway.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Oxidación-Reducción / Transducción de Señal / Proteínas Serina-Treonina Quinasas / Arabidopsis / Proteínas de Arabidopsis / Proteínas F-Box / Ácidos Indolacéticos Idioma: En Revista: Mol Plant Asunto de la revista: BIOLOGIA MOLECULAR / BOTANICA Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Oxidación-Reducción / Transducción de Señal / Proteínas Serina-Treonina Quinasas / Arabidopsis / Proteínas de Arabidopsis / Proteínas F-Box / Ácidos Indolacéticos Idioma: En Revista: Mol Plant Asunto de la revista: BIOLOGIA MOLECULAR / BOTANICA Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido